%0 Journal Article
%T Outcomes of Newborns Exposed to Human Immunodeficiency Virus/Viral Hepatitis B Co-Infection Attended at A Referral Hospital in Abidjan
%A Marie Evelyne Dainguy
%A Evelyne Adjokoua Kouadio
%A Kouam&#233
%A Cyprien Kouakou
%A Marie H&#233
%A l&#232
%A ne Ak&#233
%A -Assi-Konan
%A Ang&#232
%A le Kakou-Y&#233
%A dagne
%A Kouam&#233
%A Herv&#233
%A Micondo
%A Amah Madeleine Amorissani-Folquet
%J Open Journal of Pediatrics
%P 270-280
%@ 2160-8776
%D 2025
%I Scientific Research Publishing
%R 10.4236/ojped.2025.153025
%X <b>Introduction: </b>Infection with hepatitis B virus (HBV) and human immunodeficiency virus (HIV) is a public health problem worldwide, particularly in sub-Saharan Africa. The aim of the study was to determine the seroprevalence of HIV/HBV co-infection in pregnant women and to determine the outcomes of exposed newborns. <b>Methods: </b>This was a prospective longitudinal descriptive study conducted from October 2016 to March 2019 (18 months) among HIV/HBV co-infected pregnant women and their newborns in the pediatrics department of Cocody University Hospital. <b>Results: </b>Of a total of 7210 parturients, 31 were co-infected with HIV/HBV, representing a frequency of 0.4%. The mean age of the mothers was 30 years. They were not immunized against HBV (100%). The HBV viral load was more than 106 IU/L in 32.3% of them and HIV status was discovered in the delivery room in 39% of cases. Newborns were premature (51.9%) and low birth weight was noted in 22% of cases. All newborns were immunized against hepatitis B before the 12th hour of life and received ARV prophylaxis before the 72nd hour. The outcome showed a mortality rate of 29%, and for alive infants, HIV serology was negative at 18 months of life and all of them were immunized against HBV. <b>Conclusion:</b> Early well-managed care leads to preventing mother-to-child transmission of these two diseases. However, further action needs to be taken in terms of prevention.
%K Hepatitis B Virus
%K HIV
%K Co-Infection
%K Newborn
%K Antenatal Transmission
%K Abidjan
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=142192