%0 Journal Article
%T Evolution of the Level of Antibiotic Resistance of Nosocomial Germs in a Reference Neonatal Unit in Abidjan
%A Marie Evelyne Dainguy
%A Kouam&#233
%A Cyprien Kouakou
%A Augustine Djivohessoun
%A Isabelle Djoman
%A Andr&#233
%A Gro Bi
%A Mansou Amoro
%A Charl&#232
%A ne Soro
%A Prisca N&#8217
%A gatta
%A Amorissani Folquet
%J Open Journal of Pediatrics
%P 261-269
%@ 2160-8776
%D 2025
%I Scientific Research Publishing
%R 10.4236/ojped.2025.153024
%X Healthcare-associated infections (HAIs) are a major public health problem. The aim of the study was to describe the evolution of the level of resistance of germs to antibiotics. Methods: Prospective and analytical study that took place from January to April 2021 on 67 newborns suspected of bacterial infection and with a positive blood culture. Results: The mean gestational age was 35.7 weeks, 69% of patients were born vaginally, and 48% were in a level 3 maternity hospital. Prematurity (34%) and intrapartum asphyxia (24%) were the most common reasons for admission. The main germs found were <i>Staphylococcus aureus</i> (40.2%), <i>Staphylococcus Coagulase Negative</i> (28.3%), <i>Klebsiella pneumo</i><i>niae</i> (30%), <i>Aeromonas </i><i>salmonicida</i> (1.5%); 60% of <i>Staphylococcus Coagulase Negative</i> (SCNs) and 45% of <i>S</i>.<i> aureus</i> were resistant to penicillin; 75% of <i>K</i>.<i> pneumoniae</i> produced Extended-spectrum &#946;-lactamase (ESBL). Multi Antibiotic Resistant Bacteria were found in newborns who received care to help them adapt to extrauterine life (p = 0.0000) and significantly increased the risk of death (p &lt; 0.001). The mean length of hospital stay was 13.2 days, and the mortality rate was 19.4%. Conclusion: Good hand hygiene and optimal disinfection practices are necessary to limit HAI-related morbidity and mortality.
%K IAS
%K Neonatology
%K BMR
%K Antibiotic Therapy
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=142143