%0 Journal Article
%T Application of Radiomics Based on CE-T1WI and DWI in the Diagnosis of Submucosal Uterine Fibroids and Endometrial Carcinoma
%A Dazhi Nong
%A Nengli Long
%A Yuhua Guo
%A Shiwen Luo
%A Xinjuan Deng
%A Lijun Luo
%J Open Journal of Medical Imaging
%P 47-56
%@ 2164-2796
%D 2025
%I Scientific Research Publishing
%R 10.4236/ojmi.2025.152004
%X <b>Objective:</b> To explore the application value of radiomics based on CE-T1WI and DWI in the diagnosis of submucosal uterine fibroids and endometrial carcinoma. <b>Methods:</b> A total of 33 patients with pathologically confirmed endometrial carcinoma and 30 patients with submucosal uterine fibroids were selected. Their CE-T1WI and DWI imaging data were collected, and radiomics features such as arterial phase enhancement, venous phase enhancement, diffusion restriction, ADC values, and time-signal curve types were analyzed. <b>Results:</b> In the arterial phase, the number of cases with enhancement lower than the myometrium was significantly higher in the endometrial carcinoma group than in the submucosal fibroid group (<i>&#967;</i><sup>2</sup> = 22.4509, P = 0.0000), while the number of cases with slightly higher enhancement showed a statistically significant difference (<i>&#967;</i><sup>2</sup> = 13.1146, P = 0.0003). In the venous phase, the number of cases with enhancement higher than the myometrium was lower in the endometrial carcinoma group than in the submucosal fibroid group (<i>&#967;</i><sup>2</sup> = 5.1583, P = 0.0231). Regarding diffusion restriction, the number of cases with restricted diffusion was significantly higher in the endometrial carcinoma group (<i>&#967;</i><sup>2</sup> = 37.6794, P = 0.0000). Among cases with ADC values recorded, the ADC value in the endometrial carcinoma group (0.71 &#177; 0.22) was significantly lower than that in the submucosal fibroid group (1.34 &#177; 0.28) (<i>&#967;</i><sup>2</sup> = 7.1828, P = 0.0000). No significant difference was observed in the time-signal curve types between the two groups (<i>&#967;</i><sup>2</sup> = 0.6969, P = 0.4107). <b>Conclusion:</b> Radiomics features based on CE-T1WI and DWI have significant value in the diagnosis of submucosal uterine fibroids and endometrial carcinoma, providing a reliable basis for clinical diagnosis.
%K Submucosal Uterine Fibroids
%K Endometrial Carcinoma
%K Magnetic Resonance Imaging (MRI)
%K Diffusion-Weighted Imaging (DWI)
%K Contrast-Enhanced T1-Weighted Imaging (CE-T1WI)
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=141911