%0 Journal Article
%T 孕酮水平对冻融胚胎移植的妊娠结局的影响及其临床应用管理<br>The Impact of Progesterone Levels on Pregnancy Outcomes in Frozen-Thawed Embryo Transfer and Its Clinical Management Applications
%A 刘珍
%A 陈莹
%J Advances in Clinical Medicine
%P 293-298
%@ 2161-8720
%D 2025
%I Hans Publishing
%R 10.12677/acm.2025.154932
%X 冻融胚胎移植(FET)是辅助生殖技术中重要的治疗手段&#65292;孕酮作为调节子宫内膜容受性的关键激素&#65292;其水平的合理调控对FET周期的成功至关重要。本综述旨在探讨孕酮水平的作用机制、其对FET妊娠结局的影响以及临床策略。文章概述了孕酮的基本机制以及其在不同子宫内膜准备方案中的差异&#65292;探讨了孕酮水平对妊娠结局的影响&#65292;随后讨论了孕酮的个体化调整&#65292;如何根据孕酮水平调整治疗方案&#65292;以优化FET的妊娠结局&#65292;最后总结了孕酮的临床管理现状。尽管目前已有大量关于孕酮的研究&#65292;但在孕酮水平的动态监测、个体化治疗策略及孕酮与其他激素的协同作用等方面仍有待深入探讨。未来的研究应注重大样本、多中心研究的开展&#65292;以验证孕酮水平调控在FET妊娠结局中的关键作用&#65292;并为临床提供更科学的治疗方案。<br>Frozen-thawed embryo transfer (FET) is a crucial treatment method in assisted reproductive technology. Progesterone, as a key hormone that regulates endometrial receptivity, plays a vital role in the success of FET cycles. This review aims to explore the mechanisms of progesterone action, its impact on FET pregnancy outcomes, and clinical strategies. The article summarizes the basic mechanisms of progesterone and its differences across various endometrial preparation protocols. It discusses the influence of progesterone levels on pregnancy outcomes and follows with a discussion on individualized progesterone adjustments, emphasizing how to modify treatment plans based on progesterone levels to optimize FET pregnancy outcomes. Finally, the current status of progesterone clinical management is summarized. Although there is a wealth of research on progesterone, areas such as dynamic monitoring of progesterone levels, individualized treatment strategies, and the synergistic effects of progesterone with other hormones remain to be further explored. Future research should focus on large-scale, multi-center studies to verify the critical role of progesterone level regulation in FET pregnancy outcomes and provide more scientific treatment strategies for clinical practice.
%K 孕酮&#65292
%K 冻融胚胎移植&#65292
%K 妊娠结局<br>Progesterone
%K Freeze-Thaw Embryo Transfer
%K Pregnancy Outcome
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=110680