%0 Journal Article %T A Dual-Channel Prediction-Interpretation Framework with Pre-Trained Language Models and SHAP Explainability %A Hui Nie %A Xiaoyan Wu %J Journal of Computer and Communications %P 116-137 %@ 2327-5227 %D 2025 %I Scientific Research Publishing %R 10.4236/jcc.2025.133009 %X This study addresses the challenges of data noise and model interpretability in depression diagnosis by proposing an intelligent diagnostic framework based on real-world medical scenarios. Utilizing a labeled dataset of 11,188 Chinese online consultation records, we developed a dual-channel architecture integrating BERT/RoBERTa pre-trained models with the SHAP interpretability framework for depression severity classification. Experimental results demonstrated that the BERT model achieved 92% overall accuracy, with 93% accuracy specifically for severe depression detection. SHAP analysis revealed the model’s focus on clinically relevant features like suicidal tendencies and low mood, showing significant alignment with DSM-5 diagnostic criteria. The study confirms pre-trained models’ capability in extracting pathological semantics from medical texts, while the “prediction-interpretation” framework provides a technical prototype for overcoming clinical application barriers of black-box models. %K Depression Prediction %K Explainable Machine Learning %K BERT Model %K Patient Narrative %K SHAP Analysis %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=141586