%0 Journal Article
%T 生物活性材料修饰的聚醚醚酮在口腔种植领域的潜在应用
The Potential Application of Polyetheretherketone Modified by Bioactive Materials in the Field of Oral Implantology
%A 潘玥颖
%A 阿迪来·阿不拉
%A 热菲娜·吐尔逊
%A 麦合甫孜·艾山
%J Advances in Clinical Medicine
%P 608-613
%@ 2161-8720
%D 2025
%I Hans Publishing
%R 10.12677/acm.2025.153654
%X 口腔种植作为牙列缺损的重要修复方法之一，目前在临床上得到广泛应用，种植材料的优化对于种植成功具有重要意义。聚醚醚酮(polyetheretherketone, PEEK)是聚芳醚酮家族中的一种半结晶形态热塑性聚合物，相比于传统的口腔种植材料，PEEK具有与骨组织相近的弹性模量、化学稳定性和射线可透性等一系列优异的性能，能够避免金属腐蚀以及应力遮挡效应导致的骨吸收。然而，PEEK表面的生物惰性可能会导致骨结合不良以及感染等问题，不利于其在口腔种植领域的应用。因此，PEEK的表面改性日益成为研究的热点之一。研究人员探索了多种生物活性材料的改性方法，以有效增强PEEK及其复合材料的成骨和抗菌性。因此，本文主要综述了近年来生物活性材料改性后的PEEK的研究进展，对PEEK的成骨及抗菌策略进行了分析，并对改性后的PEEK在口腔种植领域的应用进行了展望。
As one of the important repair methods for dentition defects, oral implant is widely used in clinic. The optimization of implant materials is of great significance to the success of implants. Polyetheretherketone (PEEK) is a semi-crystalline thermoplastic polymer in the polyaryletherketone family. Compared with traditional oral implant materials, PEEK has a series of excellent properties such as elastic modulus, chemical stability and ray permeability similar to bone tissue, which can avoid metal corrosion and bone resorption caused by stress shielding effect. However, the biological inertia of PEEK surface may lead to problems such as poor osseointegration and infection, which is not conducive to its application in the field of oral implantology. Therefore, the surface modification of PEEK has increasingly become one of the research hotspots. Researchers have explored a variety of modification methods of bioactive materials to effectively enhance the osteogenic and antibacterial properties of PEEK and its composites. Therefore, this paper mainly reviews the research progress of PEEK modified by bioactive materials in recent years, analyzes the osteogenesis and antibacterial strategies of PEEK, and looks forward to the application of modified PEEK in the field of oral implantology.
%K 聚醚醚酮，
%K 牙种植体，
%K 表面修饰，
%K 生物活性，
%K 成骨，
%K 抗菌，
%K 弹性模量，
%K 种植材料
Polyetheretherketone (PEEK)
%K Dental Implant
%K Surface Modification
%K Biological Activity
%K Osteogenesis
%K Antibacterial
%K Elastic Modulus
%K Implant Materials
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=108955