%0 Journal Article
%T Malignant Sylvian Infarction: Epidemiological, Clinical and Prognostic Aspects at the Institute of Neurology of Simbaya, Conakry
%A Namory Camara
%A Mohamed Tafsir Diallo
%A Mal&#233
%A Dor&#233
%A Mohamed Lamine Cond&#233
%A Karimka Diawara
%A Dj&#232
%A n&#232
%A Keita
%A Fod&#233
%A Abass Ciss&#233
%J World Journal of Neuroscience
%P 84-94
%@ 2162-2019
%D 2025
%I Scientific Research Publishing
%R 10.4236/wjns.2025.151008
%X <b>Introduction: </b>Malignant sylvian infarction (MSI) is a type of ischemic stroke (ICS) usually affecting the entire territory of the middle cerebral artery (MCA) associated with significant cerebral edema and a mass. It represents about 10% of all AICs, with a mortality of up to 80%. The objectives of our study were to describe the sociodemographic profile and the main clinical manifestations and identify the prognostic factors of ISM. <b>Material and Methods: </b>We conducted a retrospective descriptive study over a 2-year period. It included patients hospitalized for cerebral infarction involving 2/3 of the ACM territory with a NIHSS score &#8805; 17 and/or a Glasgow score &lt; 9. Epidemiological, clinical and prognostic variables were listed. Any p-value &lt; 0.05 was considered statistically significant. <b>Results: </b>We collected 223 patients hospitalized for ischemic stroke, of whom 21 patients (9.4%) presented with ISM. The mean age was 57.43 &#177; 24.24 years with a male predominance (52.4%). The mean admission time was 47 &#177; 0.87 hours, and hemiplegia was the frequent neurological sign (85.7%). HBP was the common cardiovascular risk factor (76.2%). The mean NIHSS at admission was 18.38 &#177; 12.29. Respiratory distress (p-value = 0.00015), aspiration pneumonia (p-value = 0.015) and brain herniation (p-value = 0.014) were the main complications associated with mortality. <b>Conclusion:</b> ISM is associated with poor prognosis in the absence of surgical treatment. Respiratory distress, aspiration pneumonia and brain herniation are associated with high mortality.
%K Malignant Sylvian Infarction
%K Respiratory Distress
%K Aspiration Pneumonia
%K Cerebral Herniation
%K INS
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=140946