%0 Journal Article
%T 手性琥珀酸脱氢酶抑制剂类农药的活性与毒性研究
Activity and Toxicity Studies of Chiral Succinate Dehydrogenase Inhibitor Pesticides
%A 陈清扬
%A 王莹
%A 刘洋
%J Open Journal of Nature Science
%P 214-220
%@ 2330-1732
%D 2025
%I Hans Publishing
%R 10.12677/ojns.2025.132022
%X 近年来，琥珀酸脱氢酶抑制剂类杀菌剂因其强大的药效和对植物持久的保护力，以及显著的增产效果而备受农业界的广泛关注。然而随着仪器技术的不断进步，人们对手性农药的研究从传统的消旋体层面深入到更为精细的对映体层面，在此背景下，手性农药的立体选择性行为不容忽视。本文以手性琥珀酸脱氢酶抑制剂类农药为研究对象，从对映体水平开展了关于手性琥珀酸脱氢酶抑制剂类农药的生物活性以及对非靶标生物体毒性差异的综述，并归纳了琥珀酸脱氢酶抑制剂的作用机制，重点阐述了此类手性农药对映体生物活性与毒性的立体选择性差异，旨在为开发更安全、更高效的手性农药提供参考。
In recent years, succinate dehydrogenase inhibitor fungicides have attracted extensive attention in the agricultural field due to their powerful efficacy, long-lasting protective effect on plants, and significant yield-increasing effects. However, with the continuous advancement of instrumental technology, research on chiral pesticides has shifted from the traditional racemic level to a more refined enantiomer level. Against this backdrop, the stereoselective behavior of chiral pesticides cannot be ignored. This article takes chiral succinate dehydrogenase inhibitor pesticides as the research object and conducts a review on the biological activity and toxicity differences to non-target organisms of chiral succinate dehydrogenase inhibitor pesticides at the enantiomer level. It also summarizes the mechanism of action of succinate dehydrogenase inhibitor and focuses on elaborating the stereoselective differences in the biological activity and toxicity of enantiomers of such chiral pesticides, aiming to provide a reference for the development of safer and more efficient chiral pesticides.
%K 手性琥珀酸脱氢酶抑制剂类农药，
%K 氟唑菌酰羟胺，
%K 手性农药，
%K 生物活性，
%K 毒性
Chiral Succinate Dehydrogenase Inhibitor Pesticides
%K Pydiflumetofen
%K Chiral Pesticide
%K Bioactivity
%K Toxic Effect
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=108789