%0 Journal Article
%T 眼眶孤立性纤维瘤：病例报告并文献综述
Orbital Solitary Fibrous Tumor: A Case Report and Literature Review
%A 王杨宁致
%A 邵珺
%A 蔡季平
%J Hans Journal of Ophthalmology
%P 21-27
%@ 2167-6550
%D 2025
%I Hans Publishing
%R 10.12677/hjo.2025.141003
%X 眼眶孤立性纤维瘤(Orbital solitary fibrous tumor, OSFT)是一种来自于间质性梭形细胞的罕见眼眶肿瘤，可发生于眼眶各个部位，因部位不同有不同的临床表现，可有眼球突出，运动受限，视力下降等。男女发病无明显差异，发病年龄广泛，病程较长。眼眶孤立性纤维瘤需与多种眼眶肿物相鉴别，但其临床表现和影像学特征不明显，其确诊主要依靠病理检查，免疫组化有较高的特异性。OSFT的治疗方式主要是手术切除，因其恶变和复发可能，密切随访至关重要。由于该疾病罕见，对眼眶肿物进行鉴别诊断时多被忽视，现报道一例眼眶孤立性纤维瘤患者及其诊疗过程，并且就OSFT的临床表现、影像学改变、病理特点进行分析讨论，加深对该疾病的认知，以期为同道临床诊治提供思路及参考。
Orbital solitary fibrous tumor (OSFT) is a rare orbital tumor originating from mesenchymal spindle cells, which can occur in various parts of the orbit and present with different clinical manifestations depending on the location, including proptosis, limitation of extraocular muscle movements and blurred vision. There is no significant difference in incidence between males and females. The age of onset varies widely, and the clinical course is long. Orbital solitary fibrous tumor needs to be differentiated from various orbital tumors, however, as clinical signs and radiological features are not distinctive, the histological examination plays an important role in the diagnosis, with immunohistochemistry exhibiting a higher specificity. The primary treatment modality for OSFT is surgical resection, and due to the potential for malignant transformation and recurrence, close follow-up is essential. Given the rarity of this disease, it is frequently overlooked in the differential diagnosis of orbital masses. Here, we present a case of orbital solitary fibrous tumor, including the patient’s diagnostic and treatment process, and provide an analysis and discussion of the clinical presentation, imaging findings, and pathological characteristics of OSFT. This report aims to enhance the understanding of the disease and to offer insights and references for fellow clinicians in the clinical management of similar cases.
%K 眼眶孤立性纤维瘤，
%K 手术入路，
%K 鉴别诊断
Orbital Solitary Fibrous Tumor
%K Surgical Therapy
%K Differential Diagnosis
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=108766