%0 Journal Article
%T 铁代谢异常与卵巢癌相关研究进展<br>Research Progress on the Correlation between Abnormal Iron Metabolism and Ovarian Cancer
%A 韩嘉瑶
%A 许欣
%A 焦宗久
%A 王雅丽
%A 樊玉梅
%A 周楠
%J Journal of Clinical Personalized Medicine
%P 888-894
%@ 2334-3443
%D 2025
%I Hans Publishing
%R 10.12677/jcpm.2025.41125
%X 卵巢癌具有较高的发病率及病死率&#65292;严重威胁全世界女性的健康。铁是人体必须微量元素&#65292;参与许多细胞生理过程&#65292;研究证实肿瘤细胞对铁表现为强烈的依赖&#65292;过表达铁代谢相关的蛋白质&#65292;这使得铁在肿瘤细胞内蓄积&#65292;导致其快速增殖。近年来&#65292;铁代谢在卵巢癌中发生发展的作用机制是研究的热点问题。本篇综述讨论了铁代谢异常与卵巢癌的关系&#65292;了解铁与铁代谢相关产物在卵巢癌细胞中的变化&#65292;为指导卵巢癌的诊治提供一种新的诊疗思路。<br>Ovarian cancer has a high incidence rate and mortality, which seriously threatens the health of women all over the world. Iron is an essential trace element for the human body and participates in many cellular physiological processes. Studies have shown that tumor cells exhibit a strong dependence on iron and overexpress proteins related to iron metabolism, leading to the accumulation of iron in tumor cells and rapid proliferation. In recent years, the mechanism of iron metabolism in the occurrence and development of ovarian cancer has been a hot research topic. This review discusses the relationship between abnormal iron metabolism and ovarian cancer, understanding the changes in iron and iron metabolism related products in ovarian cancer cells, and providing a new diagnostic and therapeutic approach for guiding the diagnosis and treatment of ovarian cancer.
%K 铁代谢&#65292
%K 卵巢癌&#65292
%K 铁蛋白&#65292
%K 转铁蛋白受体&#65292
%K 膜铁转运蛋白<br>Iron Metabolism
%K Oophoroma
%K Ferritin
%K Transferrin Receptor
%K Membrane Iron Transporter Protein
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=108655