%0 Journal Article %T 术前评分模型预测减瘤结局在晚期卵巢癌中的研究现状
Preoperative Scoring Models Predicting Cytoreductive Outcomes in Advanced Ovarian Cancer %A 伍硬语 %A 肖琳 %J Advances in Clinical Medicine %P 908-916 %@ 2161-8720 %D 2025 %I Hans Publishing %R 10.12677/acm.2025.152425 %X 晚期卵巢癌治疗的标准方案为初始肿瘤细胞减灭术,术后补充以铂类为基础的联合化疗,近年来新的一种治疗方案应用愈加广泛,即行新辅助化疗后再行中间型肿瘤细胞减灭术。制定治疗方案前,须由妇科肿瘤医师基于实现满意减瘤的可能性和患者机体状况进行详细评估。目前有很多研究提出了术前评分模型以判断晚期卵巢癌患者接受初次肿瘤细胞减灭术的可能性,旨在实现满意减瘤结局、不影响生存预后的同时尽量降低手术并发症发生率,包括主要评估盆腹腔播散程度的腹膜癌指数和Eisenkop评分、评估手术复杂程度的手术复杂性评分、术前经腹腔镜探查评估肿瘤负荷的Fagotii腹腔镜评分和相应的术后并发症评分系统、以术前CT为基础的Suidan评分、预测R0切除可能的R0评分,以及结合多种评分模型的综合预测模型。
The standard treatment for advanced ovarian cancer is primary debulking surgery followed by platinum-based combination chemotherapy. In recent years, a new treatment approach has become increasingly popular, which involves neoadjuvant chemotherapy followed by interval debulking surgery. Before formulating a treatment plan, a detailed assessment is necessary, based on the possibility of achieving satisfactory cytoreduction and the patient’s overall condition. Currently, many studies have proposed preoperative scoring models to predict the possibility of primary cytoreductive surgery for advanced ovarian cancer patients, aiming to achieve satisfactory cytoreduction outcomes without affecting survival prognosis while minimizing the incidence of surgical complications. These models include the peritoneal cancer index and Eisenkop score for evaluating the extent of pelvic and abdominal dissemination, the surgical complexity score for assessing the complexity of the surgery, the Fagotii laparoscopic score and the corresponding postoperative complication scoring system for evaluating tumor burden through preoperative laparoscopy, the Suidan score based on preoperative CT, the R0 score for predicting the possibility of R0 resection, and comprehensive predictive models combining multiple scoring systems. %K 晚期卵巢癌, %K 评分模型, %K 肿瘤细胞减灭术, %K 生存预后
Advanced Ovarian Cancer %K Scoring Model %K Cytoreductive Surgery %K Survival Prognosis %U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=107966