%0 Journal Article
%T Diabetes Mellitus Revealing a Rabson-Mendenhall Syndrome: A Case Report
%A Samia Bentaleb
%A Siham Belmaati Cherkaoui
%A Sana Abourazzak
%A Mustapha Hida
%J Open Journal of Endocrine and Metabolic Diseases
%P 23-28
%@ 2165-7432
%D 2025
%I Scientific Research Publishing
%R 10.4236/ojemd.2025.152003
%X Rabson-Mendenhall syndrome (RMS) is a rare autosomal recessive inherited disease marked by insulin resistance. Mutations in the insulin receptor gene seem to be the fundamental mechanism behind this type A insulin-resistant illness. Statural growth retardation, acanthosis nigricans, hypertrichosis, dysmorphia and coarse facial features, dysplastic dentition, enlarged external genitalia, postprandial hyperglycemia and paradoxical fasting hypoglycemia, severe hyperinsulinemia and potentially onset of ketoacidosis are the symptoms of this syndrome. Because there are few therapy choices for this illness and treating hyperglycemia is a difficult undertaking, a multi-disciplinary approach is crucial to managing this difficult clinical condition. We relate the case of a young male patient, after parental consent, with features of RMS suspected in the presence of dysmorphic syndrome and insulin resistance.
%K Acanthosis Nigricans
%K Insulin Resistance
%K Diabetes
%K Hereditary
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=140778