%0 Journal Article %T 前列腺癌放射组学与多组学综合研究:现状、挑战与未来方向
Integrated Research of Prostate Cancer Radiomics and Multi-Omics: Current Status, Challenges and Future Directions %A 张忠林 %A 李鑫 %J Advances in Clinical Medicine %P 860-870 %@ 2161-8720 %D 2025 %I Hans Publishing %R 10.12677/acm.2025.151116 %X 前列腺癌的精确诊断及预后评估对于优化治疗策略和改善患者结局至关重要。放射组学和多组学技术的兴起为前列腺癌的研究带来了新的视角。放射组学通过高通量提取影像图像定量特征,实现肿瘤内部异质性可视化并揭示影像图像的潜在预后生物学信息;而多组学技术通过整合基因组学、转录组学、蛋白组学和代谢组学等多维数据,为癌症的全面分析和精准治疗提供了可能性。本文综述聚焦于放射组学与多组学在前列腺癌中的研究现状,探讨了相关研究中的争议与挑战,并展望未来发展趋势。
Accurate diagnosis and prognostic assessment of prostate cancer are of paramount importance in optimizing treatment regimens and ameliorating patient outcomes. The advent of radiomics and multi-omics technologies has bestowed novel vistas upon prostate cancer research. Radiomics facilitates the visualization of intratumoral heterogeneity and unearths the latent prognostic biological information within imaging images via high-throughput extraction of quantitative features therefrom. Multi-omics technologies, by integrating multi-dimensional data including genomics, transcriptomics, proteomics, and metabolomics, furnish the feasibility for comprehensive cancer analysis and precision therapeutics. This review centers on the extant research panorama of radiomics and multi-omics within the domain of prostate cancer, delves into the disputes and hurdles extant in pertinent research, and prognosticates the forthcoming developmental trajectories. %K 前列腺癌, %K 放射组学, %K 多组学, %K 多模态
Prostate Cancer %K Radiomics %K Multi-Omics %K Multimodal %U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=105389