%0 Journal Article
%T TMEM家族在肿瘤中的研究进展<br>Research Progress of TMEM Family in Tumour
%A 谢珣
%A 陈勇
%A 黎清
%A 宁思艺
%A 向翼
%J World Journal of Cancer Research
%P 16-23
%@ 2164-9057
%D 2025
%I Hans Publishing
%R 10.12677/wjcr.2025.151003
%X TMEM (Transmembrane, TMEM)是一类整合性膜蛋白&#65292;其特点在于能够跨越整个脂质双分子层并永久地锚定其中&#65292;分布在线粒体、内质网、溶酶体以及高尔基体等细胞器的细胞膜上。在恶性肿瘤的形成、发展和扩散等关键生物学过程中&#65292;TMEM家族蛋白扮演着举足轻重的角色。这些蛋白质的作用不仅局限于肿瘤细胞的增殖、侵袭和迁移&#65292;而且还显示出成为新型肿瘤生物标记物和治疗目标的巨大潜力。本文将对TMEM蛋白在恶性肿瘤研究领域内的最新进展进行回顾和分析。<br>TMEM (Transmembrane, TMEM) is a class of integrated membrane proteins that span and permanently anchor the entire lipid bilayer and are distributed on the cell membranes of organelles such as mitochondria, endoplasmic reticulum, lysosomes and Golgi apparatus. TMEM family proteins play an important role in the formation, development and spread of malignant tumors. The role of these proteins is not limited to the proliferation, invasion and migration of tumor cells, but also shows great potential as novel tumor biomarkers and therapeutic targets. This article will review and analyze the latest progress of TMEM protein in the field of malignant tumor research.
%K TMEM&#65292
%K 蛋白&#65292
%K 生物标志物&#65292
%K 肿瘤<br>TMEM
%K Protein
%K Biomarker
%K Tumour
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=104812