%0 Journal Article
%T Effects of Acetic Acid Bacteria (<i>Gluconacetobacter hansenii</i> GK-1) on Fatigue Induced by Temporary Mental Stress: A Randomized, Double-Blind, Placebo-Controlled Study
%A Wei Wang
%A Mariko Oe
%A Mengwei Yuan
%A Keiko Kuriyama
%A Yumi Takeda
%A Mamoru Kimura
%A Ryosuke Matsuoka
%A Kiichi Sugiyama
%A Naoki Miura
%J Food and Nutrition Sciences
%P 44-54
%@ 2157-9458
%D 2025
%I Scientific Research Publishing
%R 10.4236/fns.2025.161003
%X <b>Objective:</b> This study assessed the effects of consuming acetic acid bacteria (<i>Gluconacetobacter hansenii</i> GK-1) for 12 weeks on fatigue induced by temporary mental stress. <b>Methods:</b> This randomized, double-blind, placebo-controlled, parallel-group study included 100 healthy male and female adults aged 20 - 64 years. Participants consumed either the <i>G</i>.<i> hansenii</i> GK-1 supplement (9 &#215; 10&#8313; cells/day) or a placebo daily for 12 weeks. The impact of temporary mental stress on fatigue in <i>G</i>.<i> hansenii</i> GK-1 was assessed using a Visual Analog Scale (VAS) before the study began and after 12 weeks of supplementation. <b>Results:</b> Subjective fatigue measured by Visual Analog Scale (VAS) showed a significant decrease in fatigue induced by temporary mental stress after 12 weeks of consumption in the <i>G</i>.<i> hansenii</i> GK-1 group compared with the placebo group. No adverse events were attributed to <i>G</i>.<i> hansenii</i> GK-1. These findings confirm that continuous oral ingestion of <i>G</i>.<i> hansenii</i> GK-1 by healthy Japanese adults reduces feelings of fatigue caused by temporary mental stress.
%K Acetic Acid Bacteria
%K <i> Gluconacetobacter hansenii</i> GK-1
%K Fatigue
%K Temporary Mental Stress
%K Double-Blind Study
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=138854