%0 Journal Article
%T Predictors of Successful Radiofrequency Ablation of Benign Thyroid Nodules: A Single Centre Analysis
%A Waswa Edgar
%A Jiangyuan Cheng
%A Esraa Atef Saad
%A Mwale Paul
%A Wu Meng
%J International Journal of Clinical Medicine
%P 16-28
%@ 2158-2882
%D 2025
%I Scientific Research Publishing
%R 10.4236/ijcm.2025.161002
%X <b>Objective</b>: To assess the predictors of successful inactivation of benign thyroid nodules using radiofrequency ablation (RFA) and the hormonal responses thereafter. <b>Methods:</b> A retrospective study conducted at Zhongnan Hospital of Wuhan University (January 2022 to January 2024) analysed thyroid tumor characteristics using B-mode ultrasound, colour Doppler imaging, and CEUS post-RFA. Thyroid hormone levels were also assessed before RFA and at 1, 3, and 6 months after the procedure. <b>Results</b>: The study involved 72 patients with benign thyroid nodules, comprising 13 males and 59 females, with a mean age of 45.8 &#177; 12.1 years. Complete inactivation was achieved in 70.8% of nodules, while 29.2% showed partial inactivation. Nodules with complete inactivation exhibited more calcification (p = 0.040), whereas those with partial inactivation demonstrated higher vascularity (p &lt; 0.001). Hormonal levels remained within normal ranges, with no significant differences between the groups. Multivariate logistic regression identified nodular vascularity (p &lt; 0.001) as an independent predictor of nodule inactivation after RFA. <b>Conclusion:</b> In conclusion, this study found that therapeutic RFA effectively achieves high rates of complete inactivation in benign thyroid nodules, with the degree of inactivation mainly influenced by nodule vascularity and calcifications.
%K Predictors
%K Radiofrequency Ablation
%K Benign
%K Thyroid Nodules
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=138872