%0 Journal Article %T Signs of Aneurysm Formation Learned from Rubber Balloon Inflation %A Fumio Nogata %A Yasunari Yokota %A Yoko Kawamura %A Hiroyuki Morita %A Yoshihiro Uno %A William R. Walsh %A Takahiko Kawamura %A Nigishi Hotta %A Kenji Kagechika %J Journal of Biosciences and Medicines %P 556-571 %@ 2327-509X %D 2024 %I Scientific Research Publishing %R 10.4236/jbm.2024.1211042 %X Aneurysms can be classified into two main types based on their shape: saccular (spherical) and fusiform (cylindrical). In order to clarify the formation of aneurysms, we analyzed and examined the relationship between external force (internal pressure) and deformation (diameter change) of a spherical model using the Neo-Hookean model, which can be used for hyperelastic materials and is similar to Hooke’s law to predict the nonlinear stress-strain behavior of materials with large deformation. For a cylindrical model, we conducted an experiment using a rubber balloon. In the spherical model, the magnitude of the internal pressure Δp value is proportional to G (modulus of rigidity) and t (thickness), and inversely proportional to R (radius of the sphere). In addition, the maximum pressure Δp (max) is reached when λ (=expanded diameter/original diameter) is approximately 1.2, and the change in diameter becomes unstable (nonlinear change) thereafter. In the cylindrical model, localized expansion occurred at λ = 1.32 (λ = 1.98 when compared to the diameter at internal pressure Δp = 0) compared to the nearby uniform diameter, followed by a sudden rapid expansion (unstable expansion jump), forming a distinct bulge, and the radial and longitudinal deformations increased with increasing Δp, leading to the rupture of the balloon. Both models have a starting point where nonlinear deformation changes (rapid expansion) occur, so quantitative observation of the artery’s shape and size is important to prevent aneurysm formation. %K Aneurysm Formation %K Pressure-Inflation Characteristics %K Elastic Instability %K Expansion Signs %K Saccular and Fusiform %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=137756