%0 Journal Article
%T 银杏叶片治疗缺血性中风的Meta分析
Meta-Analysis of Ginkgo Biloba Leaves in the Treatment of Ischemic Stroke
%A 陈振薇
%A 谭蕊
%A 李卓岭
%A 杨东东
%J Advances in Clinical Medicine
%P 1056-1063
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/acm.2024.14112983
%X 目的：系统评价银杏叶片治疗缺血性中风的临床疗效及安全性。方法：运用系统评价方法，检索银杏叶片治疗缺血性中风的随机对照试验，筛选合格研究，评价纳入研究质量，采用异质性检验、Meta分析等方法统计相关数据。结果：24项研究符合选择标准，采用随机效应模型统计，纳入数据的总有效率，P < 0.00001，随机效应模型统计的合并RR (95% CI)为1.21 (1.14, 1.28)，RD (95% CI)为0.15 (0.11, 0.19)，提示试验组患者的总有效率显著高于对照组，两组比较差异有统计学意义。结论：现有证据显示，银杏叶片有益于改善缺血性中风的神经功能缺损程度，银杏叶片存在出现腹痛、腹部不适、全身皮肤瘙痒等不良反应的风险，但临床上这类报道较少。
Objective: To systematically evaluate the clinical efficacy and safety of ginkgo biloba leaves in the treatment of ischemic stroke. Methods: The randomized controlled trials of Ginkgo biloba leaves in the treatment of ischemic stroke were searched by systematic evaluation method, qualified studies were screened, the quality of the studies was evaluated, and the relevant data were collected by heterogeneity test and Meta-analysis. Results: 24 studies met the selection criteria. Using a random effects model for statistics, the total effective rate included in the data shows P < 0.00001. The combined RR (95% CI) from the random effects model is 1.21 (1.14, 1.28), and RD (95% CI) is 0.15 (0.11, 0.19), suggesting that the total effective rate of patients in the experimental group is significantly higher than that of the control group, and the difference between the two groups is statistically significant. Conclusion: The existing evidence shows that ginkgo biloba leaves are beneficial in improving the degree of neurological impairment of ischemic cerebrovascular disease, but ginkgo biloba leaves have the risk of adverse reactions such as abdominal pain, abdominal discomfort and systemic skin itching, but there are few such reports in clinic.
%K 银杏叶片，
%K 缺血性中风，
%K 脑梗死，
%K 系统评价，
%K 随机对照试验，
%K 临床疗效
Ginkgo Biloba Leaves
%K Ischemic Stroke
%K Cerebral Infarction
%K Systematic Evaluation
%K A Randomized Controlled Trial
%K Clinical Effects
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=100424