%0 Journal Article
%T 吡美莫司乳膏维持治疗特应性皮炎的临床研究<br>Clinical Study on Maintenance Treatment of Atopic Dermatitis with Pimecrolimus Cream
%A 孙明强
%J Advances in Clinical Medicine
%P 967-971
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/acm.2024.14102754
%X 目的&#65306;评价吡美莫司在特应性皮炎维持治疗中的作用。方法&#65306;74例AD病变缓解的患者随机接受1%吡美莫司乳膏或润肤剂4周的治疗。在研究结束时测量所有随机患者的湿疹面积和严重程度指数&#65292;评估复发率。结果&#65306;在研究结束时&#65292;复发患者吡美莫司乳膏治疗组中占24.3% (9/37)&#65292;而在润肤剂组中占62.2% (23/37)&#65292;差异有统计学意义。两组间均无不良反应发生。结论&#65306;局部外用吡美莫司能够抑制皮肤炎症浸润复发&#65292;可有效维持AD缓解&#65292;安全性较好。<br>Objective: To evaluate the efficacy of pimecrolimus in maintenance therapy for atopic dermatitis. Method: 74 patients with relieved AD were randomly treated with 1% pimecrolimus cream or moisturizer for 4 weeks. Measure the eczema area and severity index of all randomized patients at the end of the study to evaluate the recurrence rate. Result: At the end of the study, 24.3% (9/37) of recurrent patients were treated with pimecrolimus cream, while 62.2% (23/37) were treated with moisturizer, with a statistically significant difference. No adverse reactions occurred between the two groups. Conclusion: Topical application of pimecrolimus can inhibit the infiltration and recurrence of skin inflammation, effectively maintain AD remission, and have fewer adverse reactions.
%K 特应性皮炎&#65292
%K 吡美莫司乳膏&#65292
%K 维持治疗&#65292
%K 安全性<br>Atopic Dermatitis
%K Pyrrolimus Cream
%K Maintenance Therapy
%K Security
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=98389