%0 Journal Article
%T 白藜芦醇对PCOS的调节作用及相关机制研究进展<br>Research Progress on Regulatory Effects and Related Mechanism of Resveratrol on PCOS
%A 刘莹
%A 林欣予
%A 高爱娣
%A 王浩
%A 沈文娟
%J Advances in Clinical Medicine
%P 136-145
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/acm.2024.14102631
%X 多囊卵巢综合征是临床导致育龄期女性不孕最常见的一种生殖内分泌疾病&#65292;其发病机制尚不清楚。流行病学调查显示&#65292;本病患病率逐年上升&#65292;患病群体趋于年轻化&#65292;严重影响女性身心健康。白藜芦醇作为一种天然类雌激素&#65292;具有降糖降脂、抗炎抗氧化、抗肿瘤、心脏保护等多方面药理作用。最近研究发现&#65292;白藜芦醇可能通过多途径多靶点影响糖脂代谢及激素调节&#65292;这为临床治疗PCOS提供了新思路。笔者结合近几年国内外研究&#65292;探讨白藜芦醇对多囊卵巢综合征的调节作用&#65292;分析其作用机制&#65292;为白藜芦醇在多囊卵巢综合征治疗方面提供进一步的理论基础和研究依据。<br>Polycystic ovary syndrome is the most common reproductive endocrine disease causing infertility in women of childbearing age, and its pathogenesis is still unclear. Epidemiological surveys show that the prevalence of this disease is increasing year by year, and the group of patients tends to be younger, which seriously affects women&#8217;s physical and mental health. As a natural estrogen, resveratrol has various pharmacological effects such as hypoglycemic and hypolipidemic, anti-inflammatory and antioxidant, anti-tumor and cardioprotective effects. Recent studies have found that resveratrol may affect glucose-lipid metabolism and hormone regulation through multiple pathways and targets, which provides new ideas for the clinical treatment of PCOS. The author combines domestic and international studies in recent years to explore the regulatory effects of resveratrol on polycystic ovary syndrome (PCOS) and analyze its mechanism of action, so as to provide further theoretical foundation and research basis for resveratrol in the treatment of PCOS.
%K 白藜芦醇&#65292
%K 多囊卵巢综合征&#65292
%K 作用机制&#65292
%K 综述<br>Resveratrol
%K Polycystic Ovary Syndrome
%K Mechanism of Action
%K Review
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=97468