%0 Journal Article
%T 肺炎支原体肺炎患儿外周血NST水平与病情严重程度的相关性研究<br>Study on the Correlation between NST Levels in Peripheral Blood and the Severity of Mycoplasma Pneumoniae Pneumonia in Children
%A 廖桂梅
%A 张丽洁
%J Advances in Clinical Medicine
%P 1413-1419
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/acm.2024.1472161
%X 目的：探讨肺炎支原体肺炎(mycoplasma pneumoniae pneumonia, MPP)患儿外周血中性杆状核粒细胞(neutrophilic stab granulocyte, NST)水平与病情严重程度的相关性。方法：选取2023年9月~2024年2月陕西省人民医院152例肺炎支原体肺炎患儿为研究对象，根据病情分为轻症组(<i>n</i> = 100)和重症组(<i>n</i> = 52)。比较两组外周血NST水平。采用Spearman相关性检验分析外周血NST与C-反应蛋白(C-reactive protein, CRP)、乳酸脱氢酶(lactate dehydrogenase, LDH)、D-二聚体(D-dimer, D-D)、降钙素原(procalcitonin, PCT)水平的相关性。结果：重症组患儿外周血NST、CRP、LDH、D-D和PCT水平显著高于轻症组，差异具有统计学意义(均<i>P</i> &lt; 0.05)。重症组患儿外周血NST水平与CRP (<i>r</i> = 0.373, <i>P</i> &lt; 0.05)、D-D (<i>r</i> = 0.266, <i>P</i> &lt; 0.05)、PCT (<i>r</i> = 0.473, <i>P</i> &lt; 0.05)水平呈正相关。结论：重症肺炎支原体肺炎患儿外周血NST水平升高，与肺炎支原体肺炎疾病病情严重程度有关。<br />
Objective: To investigate the correlation between the level of neutrophilic stab granulocyte (NST) in peripheral blood of mycoplasma pneumoniae pneumonia (MPP) and the severity of the disease. Methods: 152 children with mycoplasma pneumoniae pneumonia in Shaanxi Provincial People’s Hospital from September 2023 to February 2024 were selected as the study object. They were divided into mild group (<i>n</i> = 100) and severe group (<i>n</i> = 52) according to their disease conditions. The levels of NST in peripheral blood of the two groups were compared. Spearman correlation test was used to analyze the correlation between NST and C-reactive protein (CRP), lactate dehydrogenase (LDH), D-dimer (D-D) and procalcitonin (PCT) levels were evaluated. Results: The levels of NST, CRP, LDH, D-D and PCT in peripheral blood of children in severe group were significantly higher than those in mild group, with statistical significance (all <i>P</i> &lt; 0.05). There was a positive correlation between peripheral blood NST level and CRP (<i>r</i> = 0.373, <i>P</i> &lt; 0.05), D-D (<i>r</i> = 0.266, <i>P</i> &lt; 0.05) and PCT (<i>r</i> = 0.473, <i>P</i> &lt; 0.05) levels in the severe group. Conclusions: The increase of NST level in peripheral blood of children with severe mycoplasma pneumoniae pneumonia is related to the severity of the disease.
%K 重症肺炎支原体肺炎，中性杆状核粒细胞，C-反应蛋白，乳酸脱氢酶，D-二聚体，降钙素原<br>Severe Mycoplasma Pneumoniae Pneumonia
%K Neutrophilic Stab Granulocyte
%K C-Reactive Protein
%K Lactate Dehydrogenase
%K D-Dimer
%K Procalcitonin
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=92562