%0 Journal Article
%T Positive Effect of Transcranial Direct Current Stimulation on Visual Verbal Working Memory in Patients with Attention-Deficit/Hyperactivity Disorder
%A Tomoko Uchida
%A Daisuke Matsuzawa
%A Tadashi Shiohama
%A Katsunori Fujii
%A Akihiro Shiina
%A Masamitsu Naka
%A Katsuo Sugita
%A Eiji Shimizu
%A Naoki Shimojo
%A Hiromichi Hamada
%J Open Journal of Psychiatry
%P 334-346
%@ 2161-7333
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojpsych.2024.144019
%X Background: Working memory is an executive function that plays an important role in many aspects of daily life, and its impairment in patients with attention-deficit/hyperactivity disorder (ADHD) affects quality of life. The dorsolateral prefrontal cortex (DLPFC) has been a good target site for transcranial direct current stimulation (tDCS) due to its intense involvement in working memory. In our 2018 study, tDCS improved visual-verbal working memory in healthy subjects. Objective: This study examines the effects of tDCS on ADHD patients, particularly on verbal working memory. Methods: We conducted an experiment involving verbal working memory of two modalities, visual and auditory, and a sustained attention task that could affect working memory in 9 ADHD patients. Active or sham tDCS was applied to the left DLPFC in a single-blind crossover design. Results: tDCS significantly improved the accuracy of visual-verbal working memory. In contrast, tDCS did not affect auditory-verbal working memory and sustained attention. Conclusion: tDCS to the left DLPFC improved visual-verbal working memory in ADHD patients, with important implications for potential ADHD treatments.
%K Working Memory
%K Attention-Deficit/Hyperactivity Disorder
%K Dorsolateral Prefrontal Cortex
%K Transcranial Direct Current Stimulation
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=134635