%0 Journal Article
%T Preliminary Study on Occult Hepatitis B in Sickle Cell Anemia
%A Maurice Mambu Kalonji
%A Steve Dibere Kodondi
%A Bijou Tsholuka Bondo
%A Blaise Matondo Manzambi Sumbu
%A Paulin Beya Mutombo
%A Guylain Kawali Nyembo
%A Excellence Ngbo Tongu
%A Mireille Lelo Babazanga
%A Caddy Nsenga Ngoie
%A Tite Minga Mikobi
%A Fridolin Kule Koto Kodondi
%A Steve Mundeke Ahuka
%J Open Access Library Journal
%V 11
%N 9
%P 1-9
%@ 2333-9721
%D 2024
%I Open Access Library
%R 10.4236/oalib.1111902
%X <strong>Introduction:</strong> The transmission of occult hepatitis B Virus (HBV) is a significant public health issue among transfused sickle cell disease (SCD) patients. <strong>Object</strong>: The aim of this study was to determine the prevalence of occult hepatitis B in SCD patients and to establish the association between HBsAg and anti HBc, according to the number of blood transfusions received. <strong>Patients and Methods:</strong> This epidemiological, descriptive and analytical study was conducted in three sickle cell care centers in Kinshasa from January to June 2018, involving 384 transfused SCD patients. <strong>Results:</strong> The study revealed that the age group 10 - 20 years was the most represented with a predominance of males (male-female sex ratio of 1.07). 65 patients of the study population tested positive for anti-HBc but negative for HbsAg and had occult hepatitis, representing 19.0 % of the total.&nbsp;<strong>Conclusion:</strong> Occult hepatitis B is a particular form of HBV infection that is increasingly attracting the attention of clinicians in the SCD patients.
%K Occult Hepatitis B
%K Sickle Cell Disease
%K Transfusion
%K Elisa
%K Determine
%U http://www.oalib.com/paper/6831177