%0 Journal Article
%T Molecular Detection of Resistance and Virulence Genes in Coagulase Negative Staphylococci Isolated from Blood Cultures at the University Teaching Hospital of Bouake
%A Oby Z&#233
%A phirin Wayoro
%A Ahou Micheline N&#8217
%A Guessan
%A Adjaratou Traore
%A Akissi Christine Houssou
%A Etil&#233
%A Augustin Anoh
%A Abdoulaye Diarrassouba
%A Safiatou Karidioula
%A Juste Olivier Tadet
%A Pac&#244
%A me Monemo
%A Chantal Akoua-Koffi
%J Journal of Biosciences and Medicines
%P 52-63
%@ 2327-509X
%D 2024
%I Scientific Research Publishing
%R 10.4236/jbm.2024.126007
%X <b>Introduction: </b>Coagulase-negative staphylococci (CoNS) are currently recognized as genuine pathogens. However, little is known about the resistance and virulence genes that explain their pathogenicity in hospitals in Côte d'Ivoire. The aim of this study was to contribute to the genotypic identification of resistance and virulence genes in CoNS isolated from blood cultures at the University Teaching Hospital (CHU) of Bouaké, in order to improve patient management. <b>Material and Methods:</b> This was a descriptive study conducted from September to December 2023. The CoNS isolates studied came from the collection of strains isolated from blood cultures of febrile patients hospitalized or attending consultations at the CHU of Bouaké. The strains were analyzed using conventional simplex PCR. <b>Results</b>: Of the 45 isolates analyzed, 46.7% carried both the <i>aacA-aphD </i>and<i> tetK </i>genes<i> and </i>40% carried the <i>mecA</i> gene. With regard to virulence genes, only the <i>LukS-PV</i> gene was observed in <i>S. epidermidis and S. haemolyticus</i> isolates. <b>Conclusion</b><b>:</b> The<i> </i>high prevalence of CoNS isolates carrying the <i>mecA</i> gene and the presence of virulence genes observed in this study give cause for concern in hospitals. It is important to develop comprehensive surveillance strategies against nosocomial and multi-resistant infections at the CHU of Bouaké.
%K Coagulase-Negative Staphylococcus
%K Gene
%K Multiresistance
%K Virulence
%K Bouak&amp
%K #233
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=133744