%0 Journal Article %T Origin and Basic Mechanism of Life %A Jan Helm %J Open Journal of Biophysics %P 265-329 %@ 2164-5396 %D 2024 %I Scientific Research Publishing %R 10.4236/ojbiphy.2024.143011 %X This paper presents in a concise way the main characteristics of life from the physical point of view and the most successful theories of biogenesis, together with a mathematical formulation and simulation of proto-biogenesis. We present here a calculation method for biochemical reactions based on the available reaction data base, and using this method, we calculate precise scenarios for the first life cycle, and for the first stages of terrestrial biological evolution. %K Proto-Life-Cycle %K Prebiotic Evolution %K PNA World %K Genetic Proto-Code %K LUCA %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=133696