%0 Journal Article
%T Calculating the Crystallite Size of <i>Microsorum scolopendria</i> AgCl Nanoparticles and Their Biological Activities
%A Christian Nanga Chick
%A Mohammed Mahdaly
%A Phillippe Belle Ebanda Kedi
%A Kiuchi Sonoko
%A Francois Eya&#8217
%A ane Meva
%J Journal of Biomaterials and Nanobiotechnology
%P 25-37
%@ 2158-7043
%D 2024
%I Scientific Research Publishing
%R 10.4236/jbnb.2024.152002
%X In this work, AgCl nanoparticles were synthesized from <i>Microsorum scol</i><i>o</i><i>pendria</i> (MS) aqueous extract and AgNO<sub>3</sub> solution. Preliminary confirmation was a color change from a light brown to a dark-colored solution and a UV-Vis spectra surface plasmon resonance peak at 427 nm. Measured vibrational frequencies at 1713 cm<sup>−1</sup> and 1030 cm<sup>−1</sup> for C-O stretching of carboxylic acid or aliphatic ketone, and 1547 cm<sup>−1</sup> for possibly N-O stretching of nitro compounds by Infrared (FTIR) analysis explain the possible biomaterial electronegative species or functional groups responsible for the reduction of Ag ( 1) to Ag (0) for the formation of MS-AgCl nanoparticles. XRD analysis studies revealed that these particles contained face-centered cubic crystallites of metallic AgCl of 100 % with an average calculated crystallite size range of 30.34 nm (<i>SD</i> = 5.10 nm) by Scherrer’s equation and a calculated crystallite size of 66.04 nm with a lattice strain of 0.00175 nm by Williamson Hall equation. The measured albumin denaturing activity of MS-AgCl nanoparticles gave an IC<sub>50 </sub>value of 26.70 µg/mL and 1.35 µg/mL for the positive control diclofenac. Additionally, the measured ability of phosphomolybdate complex formation, the antioxidant IC₅₀ value of MS-AgCl nanoparticles was 35.29 µg/mL, and positive control ascorbic acid was 13.91 µg/mL<i>.</i> In all, using MS fern frond aqueous extracts, this preliminary work confirms MS<i>-</i>AgCl nanoparticles as potential therapeutic agents for oxidative stress, inflammatory problems, and related diseases.
%K &lt
%K i&gt
%K Microsorum scolopendria&lt
%K /i&gt
%K SNPs
%K IR
%K UV-Vis
%K Antioxidant
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=133499