%0 Journal Article
%T Surgical Management of Perforated Colon Tumours in Yaound&amp;#233;: A Multicentre Retrospective Review of 30-Day Postoperative Outcome
%A Eric Patrick Savom
%A Richard II Mbele
%A Colman Tamboh Tankou
%A Mahamat Yannick Ekani Boukar
%A C&#233
%A dric Paterson Atangana
%A Fred Dikongue Dikongue
%A Daniel Biwole Biwole
%A Guy Aristide Bang
%A Arthur Essomba
%J Surgical Science
%P 330-341
%@ 2157-9415
%D 2024
%I Scientific Research Publishing
%R 10.4236/ss.2024.155031
%X &lt;b&gt;Introduction&lt;/b&gt;&lt;b&gt;: &lt;/b&gt;Colon cancer is often diagnosed late in our context and there is a high prevalence of complicated forms, this including perforation. The optimal surgical treatment remains controversial. The aim of this study was to improve the short-term postoperative outcomes of patients operated upon for perforated colon cancer, by identifying factors associated with complications occurring within 30 days after surgery. &lt;b&gt;Patients&lt;/b&gt; &lt;b&gt;and&lt;/b&gt; &lt;b&gt;methods&lt;/b&gt;&lt;b&gt;: &lt;/b&gt;We carried out an analytical observational study, with a retrospective collection of data from the files of patients operated upon for an &lt;i&gt;in&lt;/i&gt; &lt;i&gt;situ&lt;/i&gt; tumoral colon perforation. This was done in four referral hospitals in the city of Yaound&amp;#233;. The period was from the 1&lt;sup&gt;st&lt;/sup&gt; of January, 2012 to the 31&lt;sup&gt;st&lt;/sup&gt; of December, 2021. Cox regression identified the factors associated with postoperative morbidity and mortality. &lt;b&gt;Results&lt;/b&gt;&lt;b&gt;: &lt;/b&gt;We collected files of 46 patients. The mean age was 54.7 &amp;#177; 19.9 years with a sex ratio of 1.4. The clinical presentation on admission was dominated by the presence of signs of peritoneal irritation (91.3%) and bowel obstruction (28.3%). The diagnosis was made preoperatively in 16 cases (34.8%). The surgical procedures consisted of colectomy with anastomosis in 28 cases (60.9%) and without anastomosis in 14 cases (30.4%). Postoperative morbidity was 60.9% dominated by surgical site infection (37%). Postoperative mortality was 39.1%. The existence of generalized peritonitis was associated with the occurrence of postoperative complications (p = 0.019). The main factors associated with postoperative mortality were resection with primary anastomosis (p = 0.027), enterocutaneous fistula (p = 0.005). &lt;b&gt;Concl&lt;/b&gt;&lt;b&gt;u&lt;/b&gt;&lt;b&gt;sion&lt;/b&gt;&lt;b&gt;: &lt;/b&gt;Colic resection with primary anastomosis or ideal colectomy is associated with an increased risk of mortality and should therefore not be performed in this setting.
%K Perforated Colon Cancer
%K Postoperative Morbidity and Mortality
%K Colectomy
%K Acute Generalized Peritonitis
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=133118