%0 Journal Article
%T 成人噬血细胞综合征的诊疗<br>Diagnosis and Treatment of Adult Hemophagocytic Syndrome
%A 高柯迪
%A 娄世锋
%J Advances in Clinical Medicine
%P 416-421
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/acm.2024.1451443
%X 噬血细胞综合症(HLH)是一种以高免疫反应为特征的危及生命的疾病。临床表现为持续发热、脾大、血细胞减少、高甘油三酯血症、低纤维蛋白原血症和高铁蛋白血症。其发病机制是遗传基因突变和外在触发因素的结合。成人HLH用皮质类固醇联合或不联合依托泊苷治疗是主要的治疗方法。<br />
Hemophagocytic syndrome (HLH) is a life-threatening disease characterized by a high immune response. The clinical manifestations include persistent fever, splenomegaly, decreased blood cells, hypertriglyceridemia, hypofibrinogenemia, and ferritinemia. The pathogenesis is a combination of genetic mutations and external triggering factors. The main treatment method for adult HLH is the combination or non combination of corticosteroids and etoposide.
%K 噬血细胞综合征，噬血性淋巴组织细胞增生症，巨噬细胞活化综合征<br>Hemophagocytic Syndrome
%K Hemophagocytic Lymphohistiocytosis
%K Macrophage Activation Syndrome
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=86378