%0 Journal Article
%T 中医特色疗法治疗肥胖型多囊卵巢综合征Meta分析
Meta-Analysis of Traditional Chinese Medicine in the Treatment of Obese Polycystic Ovary Syndrome
%A 孙小惠
%A 韩亚光
%A 张欣
%A 朱小琳
%J Advances in Clinical Medicine
%P 390-400
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/acm.2024.1451439
%X 目的:系统评价单纯中医特色疗法治疗肥胖型多囊卵巢综合征的临床作用及其安全性。方法:在知网(CNKI)、万方(WanFang)、维普(VIP)、PubMed、CochraneLibrary、Embase数据库中检索了自建库至2023年1月7日为止发表的关于中医特色疗法治疗肥胖型PCOS患者的临床研究文章,最终纳入文献数量为12篇,共851例患者,其中中医特色疗法组426例,对照组425例,提取数据,总结文献特征和评估文献偏倚风险;然后采用RevMan5.4软件进行Meta分析。结果:比较两组总有效率、BMI、LH、睾酮、LH/FSH值、不良反应发生率方面治疗组疗效优于对照组,差异具有统计学意义(P < 0.05),比较两组促卵泡激素(FSH)、胰岛抵抗指数和改善月经方面,两组差异无统计学意义(P > 0.05)。结论:与单纯药物治疗相比,中医特色疗法在改善肥胖型PCOS患者的临床症状,BMI指数和性激素水平方面疗效更佳。
Objective: To evaluate the clinical effect and safety of traditional Chinese medicine in the treatment of obese polycystic ovary syndrome. Methods: Clinical research articles on the treatment of obese PCOS patients with traditional Chinese medicine were retrieved from CNKI, WanFang, VIP, PubMed, Cochrane Library and Embase databases since the establishment of the search database until January 7, 2023. A total of 851 patients were included in 12 literatures, including 426 patients in the TCM characteristic therapy group and 425 patients in the control group. Data were extracted to summarize the literature characteristics and assess the risk of literature bias. Then, meta analysis was performed using RevMan5.4 software. Results: The total effective rate, BMI, LH, testosterone, LH/FSH values and incidence of adverse reactions were compared between the two groups, and the curative effect of the treatment group was better than that of the control group, with statistical significance (P < 0.05), while there was no statistical significance between the two groups in follicle stimulating hormone (FSH), islet resistance index and menstrual improvement (P > 0.05). Conclusion: Compared with drug therapy alone, TCM characteristic therapy is more effective in improving the clinical symptoms, BMI and sex hormone levels of obese PCOS patients.
%K 中医特色,肥胖,多囊卵巢综合征,Meta分析
TCM Characteristics
%K Obesity
%K Polycystic Ovary Syndrome
%K Meta-Analysis
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=86374