%0 Journal Article
%T 经鼻高流量湿化氧疗对慢阻肺合并慢性左心衰竭患者的疗效观察
Observation on Efficacy of High-Flow Nasal Cannula Oxygen Therapy in Patients with COPD with Chronic Left Heart Failure
%A 王晓斐
%A 张雪娟
%J Advances in Clinical Medicine
%P 1654-1659
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/acm.2024.1441205
%X 目的：分析高流量湿化氧疗对慢阻肺合并慢性左心衰患者的治疗效果。方法：选取2021年8月至2023年8月于青岛大学附属医院全科医学科及临沭县人民医院呼吸与危重症医学科住院治疗的慢阻肺合并心衰患者60例，随机分为两组，命名观察组(n = 30)、对照组(n = 30)，在采取常规药物治疗的同时，对照组采用普通鼻导管吸氧治疗，观察组采用高流量湿化治疗仪完成氧疗治疗，观察两种治疗方案治疗的呼吸及心脏相关指标。结果：两组患者第5天观察指标较第1天均有明显改善，且数据有显著统计学差异(P < 0.05)。入院第3天及第5天，观察组CAT评分及NT-proBNP数值较对照组明显降低，差异有统计学意义(P < 0.05)。入院第3天和第5天，观察组及对照组患者的心率、舒张压、脉搏血氧饱和度及动脉二氧化碳分压的差异无统计学意义(P > 0.05)。入院第3天观察组患者的收缩压数值较对照组升高(P < 0.05)。第5天，观察组及对照组患者的收缩压数值差异无统计学意义(P > 0.05)。入院第3天和第5天，观察组患者动脉血氧分压显著高于对照组，差异有统计学意义(P < 0.05)。结论：经鼻高流量湿化氧疗在慢阻肺合并慢性左心衰竭患者中应用，可更快地改善呼吸道症状，降低NT-proBNP改善心功能，使患者更快地取得疗效。
Objective: To analyze the therapeutic effect of high-flow humidification oxygen therapy in patients with COPD and chronic left heart failure. Methods: Selected from August 2021 to August 2023 in the General Practice of the Affiliated Hospital of Qingdao University and the PCCM of Linshu County People’s Hospital of COPD with heart failure patients 60 patients, randomly divided into two groups, named observation group (n = 30), control group (n = 30), while taking conventional drug treatment, the control group with ordinary nasal catheter oxygen therapy, observation group with high flow humidification treatment oxygen therapy treatment, observe the respiratory and cardiac related indicators of two treatment options. Results: Both were improved on day 5 compared with day 1, and the data were statistically different (P < 0.05). On day 3 and day 5 of admission, the CAT score and NT-proBNP values were significantly lower in the control group, with a statistically significant difference (P < 0.05). On admission day 3 and day 5, heart rate, diastolic pressure, pulse oxygen saturation and arterial CO pressure were not significantly different between the observation and control groups (P > 0.05). SBP values in the observation group on admission Day 3 were higher compared with the control group (P < 0.05). On Day 5, there was no significant difference in SBP values between the observation and control groups (P > 0.05). On day 3 and day 5 of admission, the arterial partial oxygen pressure in the observation group was significantly higher than the control group, which was significant (P < 0.05). Conclusion: The application of transnasal high-flow humidification oxygen therapy in patients with COPD combined with chronic left heart failure can improve respiratory symptoms faster, reduce NT-proBNP to improve cardiac function, and make patients achieve efficacy more quickly.
%K 经鼻高流量湿化氧疗，慢性阻塞性肺疾病(COPD)，心力衰竭，疗效
High-Flow Nasal Cannula Oxygen Therapy (HFNC)
%K Chronic Obstructive Pulmonary Disease (COPD)
%K Heart Failure (HF)
%K Therapeutic Effect
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=85084