%0 Journal Article
%T Profile of Multidrug Resistant Bacteria in Bukavu Hospitals and Antimicrobial Susceptibility to &lt;i&gt;Escherichia coli&lt;/i&gt;, &lt;i&gt;Pseudomonas aeruginosa&lt;/i&gt;, &lt;i&gt;Proteus mirabilis and Staphylococcus aureus&lt;/i&gt;
%A Christian Ahadi Irenge
%A Freddy Bikioli
%A Patient Birindwa Mulashe
%A F&#233
%A licien Mushagalusa Kasali
%A Patient Wimba
%A Aksanti Lwango
%A Yves Coppieters
%A Justin Ntokamunda Kadima
%J Advances in Microbiology
%P 209-225
%@ 2165-3410
%D 2024
%I Scientific Research Publishing
%R 10.4236/aim.2024.144015
%X &lt;b&gt;Objective: &lt;/b&gt;To evaluate the spread of Multidrug-Resistant (MDR) bacterial infections in Bukavu hospitals and test antimicrobial susceptibility patterns of some isolates to usual marketed antibiotics. &lt;b&gt;Method&lt;/b&gt;&lt;b&gt;s&lt;/b&gt;&lt;b&gt;:&lt;/b&gt; The prevalence of MDR strains was determined by using general antimicrobial susceptibility data collected from 3 hospital laboratories. The susceptibility of some isolates to usual antibiotics was processed by agar diffusion method with standard &lt;i&gt;E. coli&lt;/i&gt; ATCC8739 and standard antibiotics discs as controls. The tested antibiotics were ampicillin, ceftriaxone, gentamicin, chloramphenicol and ciprofloxacin. &lt;b&gt;Results: &lt;/b&gt;At the 3 hospitals, 758 tests were realized in urine, pus, stool, FCV, blood, LCR, split and FU specimens; 46 strains were unidentified and 712 strains were identified. Of 712 identified strains, 223 (31.4%) were MDR or XDR strains including &lt;i&gt;Escherichia coli&lt;/i&gt;,&lt;i&gt; Klebsiella pneumoniae&lt;/i&gt;,&lt;i&gt; Enter&lt;/i&gt;&lt;i&gt;o&lt;/i&gt;&lt;i&gt;bacter&lt;/i&gt;,&lt;i&gt; Proteus mirabilis&lt;/i&gt;,&lt;i&gt; Salmonella enterica&lt;/i&gt;,&lt;i&gt; Pseudomonas aeruginosa&lt;/i&gt;,&lt;i&gt; C&lt;/i&gt;&lt;i&gt;i&lt;/i&gt;&lt;i&gt;trobacter freundii&lt;/i&gt;,&lt;i&gt; Morganella morganii&lt;/i&gt;,&lt;i&gt; Enterococcus faecalis&lt;/i&gt; &lt;i&gt;and&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;E. fae&lt;/i&gt;&lt;i&gt;cium&lt;/i&gt;,&lt;i&gt; Neisseria gonorrohoae&lt;/i&gt;,&lt;i&gt; Staphylococcus aureus&lt;/i&gt;,&lt;i&gt; &lt;/i&gt;coagulase-negative, staphylococci,&lt;i&gt; Streptococcus pneumoniae&lt;/i&gt; and &lt;i&gt;Streptococcus pyogenes&lt;/i&gt;. Of the infected patients, 36 (21.5%) children were under 16 years and 188 (78.5%) adults were predominately women (58.5%). The susceptibility test showed that all strains but &lt;i&gt;S.&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;aureus&lt;/i&gt; were resistant to ampicillin and amoxicillin and ciprofloxacin. Gentamicin, ceftriaxone, and chloramphenicol remain partially active (27% - 80%) against &lt;i&gt;P.&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;mirabilis&lt;/i&gt;,&lt;i&gt; E.&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;coli&lt;/i&gt; and &lt;i&gt;P.&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;aeruginosa&lt;/i&gt;. The resistance is more likely related to strain mutation than to pharmaceutical quality of the antibiotics prescribed. &lt;b&gt;Conclusion: &lt;/b&gt;Both data from hospital laboratories and &lt;i&gt;in &lt;/i&gt;&lt;i&gt;vitro&lt;/i&gt; post-testing findings
%K Prevalence
%K Antimicrobials
%K Multi-Resistance
%K Bacterial Sensitivity
%K Bukavu
%K DRC
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=132444