%0 Journal Article
%T 卵巢癌患者的生育力保存<br>Fertility Preservation in Patients with Ovarian Cancer
%A 丁金钰
%A 徐艳斐
%J Advances in Clinical Medicine
%P 724-730
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/acm.2024.1441082
%X 随着诊断技术的进步和治疗手段的提高，卵巢癌患者幸存比例明显增加，但在癌症治疗过程中，手术及某些放化疗手段均会对卵巢功能造成不可逆转的损伤，随着卵巢癌患者生存时间的延长和生存率的提高，很多患者不得不面临生育力折损的严重问题，但人们目前对生育力保存时机、适用方法及存在的风险认识尚浅，本文结合最近研究进展，对临床常用的卵巢癌治疗手段对女性生育力产生的损伤及目前适用于卵巢癌女性的生育力保存方法进行了总结，希望能够为临床上卵巢癌患者的诊疗及生育力保存提供依据。<br />
With the advancement of diagnostic technology and improvement in treatment methods, there has been a significant increase in the survival rate of ovarian cancer patients. However, in the course of cancer treatment, certain surgical procedures, as well as radiotherapy and chemotherapy treatments, can lead to irreversible damage to ovarian function. As the survival time extends and the overall survival rate improves for ovarian cancer patients, many individuals are confronted with the serious issue of fertility loss. Unfortunately, there is still limited awareness regarding the optimal timing, suitable methods, and associated risks of fertility preservation. This review summarized recent research progress on the detrimental effects on female fertility caused by commonly used clinical treatments for ovarian cancer and present current applicable fertility preservation methods for women with this condition. We hope to provide a basis for clinical management and fertility preservation in patients with ovarian cancer.
%K 卵巢癌，治疗，DNA损伤，生育力保存<br>Ovarian Cancer
%K Treatment
%K DNA Damage
%K Fertility Preservation
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=84360