%0 Journal Article
%T 关于肿瘤表面转铁蛋白受体的药物递送进展<br>Progress in Drug Delivery via Transferrin Receptors on the Surface of Tumors
%A 胡雨凌
%A 刘煜
%J Pharmacy Information
%P 92-100
%@ 2160-4452
%D 2024
%I Hans Publishing
%R 10.12677/pi.2024.132012
%X 随着对转铁蛋白受体研究的深入，基于转铁蛋白受体的药物靶向策略得到了显著发展。由于转铁蛋白受体在多种细胞，包括肿瘤细胞中的高表达，因此被开发为抗肿瘤药物的潜在靶点。靶向肿瘤表面转铁蛋白受体进行肿瘤治疗的药物有多种开发方式，本文介绍了转铁蛋白受体配体的开发，以及以这些配体为基础进行肿瘤药物开发，这些药物在各种治疗中显示出显著的疗效。虽然目前的开发还面临着一些挑战，但进一步优化转铁蛋白受体靶向药物递送系统在实现更为精准和有效的肿瘤治疗中仍然十分重要。<br />
As research into transferrin receptors has deepened, drug targeting strategies based on transferrin receptors have seen significant development. Due to the high expression of transferrin receptors in various cells, including tumor cells, they have been developed as potential targets for anti-tumor drugs. There are various development methods for drugs that target tumor surface transferrin receptors for tumor treatment. This article introduces the development of transferrin receptor ligands, as well as tumor drug development based on these ligands, which have shown significant therapeutic effects in various treatments. Although the current development still faces some challenges, further optimization of the transferrin receptor-targeting drug delivery system remains very important in achieving more precise and effective tumor treatment.
%K 转铁蛋白受体，肿瘤，靶向治疗，药物递送<br>Transferrin Receptor
%K Tumor
%K Targeted Therapy
%K Drug Delivery
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=83489