%0 Journal Article
%T Multiplex Rapid Test with Acceptable Diagnosis Performance as a Solution to Increase Diagnosis of Hepatitis B and C Viruses in Pregnant Women in an Area of High Prevalence of Both Hepatitis Viruses Associated with HIV
%A Catherine Boni-Cisse
%A Nina Esther Onstira Ngoyi
%A Hermione Dahlia Mossoro-Kpinde
%A Noella Packo
%A Rabi Senekian
%A Hermann Ndoidet Koutou
%A Coretha Bokia-Baguida
%A Christelle Luce Bobossi-Gadia
%A Arthur Simplice Sombot-Ndicky
%A Daniel Yvon Gonessa
%A Freddy Samuel Ngbonga Konzapa Voulou
%A Christian Diamant Mossoro-Kpinde
%J Open Journal of Medical Microbiology
%P 50-65
%@ 2165-3380
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojmm.2024.141005
%X <b><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">Background</span></b><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> <b>and</b> <b>Objective:</b> HIV, hepatitis B virus (HBV) and hepatitis C virus
(HCV) are very widespread in the world, however, less than 20% of the
people affected are diagnosed and treated. This study aimed to determine the
prevalence of HIV, HCV and HBV co-infections in pregnant women at Bangui
Community University Hospital and the cost of screening. <b>Methods:</b> A
cross-sectional study involving consenting pregnant women who came for
antenatal care was performed. HIV, HCV antibodies and HBV antigen</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">s</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> were detected using Exacto Triplex<sup><span style=\"font-family:Verdana, Helvetica, Arial;text-wrap:wrap;background-color:#FFFFFF;\">?</span></sup> HIV/HCV/HBsAg rapid test,
cross-validated b<span>y ELISA tests.
Sociodemographic and professional data, the modes of transm</span>ission and
prevention of HIV and both hepatitis viruses were collected in a standard sheet
and analyzed using the Epi-Info software version 7. <b>Results:</b> Pregnant
women aged 15 to 24 were the most affected (45.3%); high school girls (46.0%), </span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">and </span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">pregnant women living in cohabitation (65.3%) were the most represented.
Twenty-five (16.7%) worked in the formal sector, 12.7% were unemployed</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> </span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">housewives</span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\"> </span><span style=\"font-size:10.0pt;font-family:;\" \"=\"\">and the remainder in the
informal sector. The prevalence of HIV, HBV, and HCV viruses was 11.8%, 21.9%
and 22.2%, respectively. The prevalence of co-infections
was 8.6% for HIV-HBV, 10.2% for HIV-HCV, 14.7% for HBV-HCV and 6.5% for
HIV-HBV-HCV. All positive res<span>ults and
10% of negative results by the rapid test were confirmed by ELISA tests. The
serology of the three viruses costs 39,000 FCFA (60 Euros) by ELISA compared to
10,000 FCFA (15.00 Euros) with Exacto Triplex<sup><span style=\"font-family:Verdana, Helvetica, Arial;text-wrap:wrap;background-color:#FFFFFF;\">?</span></sup> HIV/HCV/<i>A</i></span><i><span>gH</span>Bs</i> (BioSynex,
Strasbourg, France). <b>Conclusion:</b> The low level of education and
awareness of hepatitis are barriers to
%K HIV-HCV-HBV Co-Infection
%K Multiplex Immunochromatographic Rapid Test
%K Central Africa
%K Serology Test Cost
%K Diagnostic Accessibility
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=132115