%0 Journal Article
%T Seroprevalence of HBV and HCV among People Living with HIV in Burkina Faso and Diagnostic Performance of HIV/HCV/HBsAg Combined Rapid Test in Comparison with Architect Assays
%A Serge Theophile Soubeiga
%A Albert Theophane Yonli
%A Alain Megabtche Nantchouang
%A Jacques Simpore
%J Open Journal of Medical Microbiology
%P 1-10
%@ 2165-3380
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojmm.2024.141001
%X <b><span style=\"font-size:10.0pt;font-family:&quot;\">Background</span></b><span style=\"font-size:10.0pt;font-family:&quot;\">: The diagnosis of
human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C
virus (HCV) remains a constraint for some populations in sub-Saharan Africa.
This study aimed to determine the prevalence of HBV and HCV in people living
with HIV and to evaluate the performance of a combined rapid test for the
simultaneous detection of HIV, HBV, and HCV. <b>Methods</b>: This is a
cross-sectional study that took place from February 2017 to November 2018 and
included 139 HIV-infected individuals followed</span><span style=\"font-size:10.0pt;font-family:&quot;\"> </span><span style=\"font-size:10.0pt;font-family:&quot;\">up at different medical centers in Ouagadougou, Burkina Faso. HBV and HCV
serology tests were performed on-site using finger prick whole blood with
HIV/HCV/HBsAg combined rapid test and then serum with two reference tests
”°Architect HBsAg Qualitative”± and ”°Architect HIV Ag/Ab Combo”±. <b>Results</b>:
The mean age of the participants was 57 ”Ą 8 years. Of the 139 participants, 10%
(14/139) were HIV-1 positive, 71.9% (100/139) were HIV-2 positive, and 18.0%
(25/139) were HIV-1/HIV-2 coinfected. The sensitivity and specificity of the
HIV/HCV/HBsAg combined rapid test were 33.33% vs 99.11% and 20% vs 99.25%
compared to Architect HBsAg Qualitative and Architect HIV Ag/Ab Combo,
respectively. The Kappa and Youden Index values were 0.4262 and 0.3244 and
0.2707 and 0.1925, respectively, compared to each of the two reference tests. <b>Conclusion</b>:
The results show that the HIV/HCV/HBsAg combined rapid test has poor diagnostic
efficiency and should not be recommended for the diagnosis of these viruses.</span>
%K HIV
%K HBV
%K HCV
%K Prevalence
%K Diagnosis
%K Burkina Faso
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=132106