%0 Journal Article
%T Serological Profile of Hepatitis D Virus (Hepatitis Delta) in the Hepato-Gastro-Enterology Department of Chu Gabriel Toure
%A Sanra D¨¦borah Sanogo
%A Kadiatou Doumbia
%A Hourouma Sow
%A Moussa Younoussou Dicko
%A Youssouf Oumarou
%A Abdoulaye Berth¨¦
%A Sabine Drabo
%A Luc Sidib¨¦
%A Makan Sir¨¦ Tounkara
%A Abdoulaye Maiga
%A Ouatou Mall¨¦
%A Ganda Soumar¨¦
%A Anselme Konat¨¦
%A Moussa Ti¨¨moko Diarra
%J Open Journal of Gastroenterology
%P 93-98
%@ 2163-9469
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojgas.2024.143010
%X Infection with the defective hepatitis D virus (HDV) co-infects or superinfects a patient carrying hepatitis B virus (HBV). Delta virus infection is relatively common. The seriousness of infection with the hepatitis D virus (HDV), a virus defective in a patient carrying the hepatitis B virus (HBV), lies in its aggravating effect on the associated viral hepatitis B. Our aim was to study the serological profile of HDV in HBsAg-positive patients. As this study was fragmentary, we initiated this study with the aim of investigating the serological profile of HDV in HBsAg-positive patients. This was a descriptive and analytical cross-sectional study that ran from March 2019 to February 2020, a 12-month period. It focused on the population of patients seen and screened positive for HBsAg. We obtained a frequency of 10%. The mean age of our patients was 41.8 ˇŔ 13.09 years. The sex ratio was 4.5. VHD RNA was detected in 50% of patients. In 100% of cases, the presence of VHD RNA was associated with advanced fibrosis according to the APRI score, but without any statistically significant link. All HBV-infected patients should be screened for anti-HDV Ac. HDV infection leads to rapid progression to complications of liver disease.
%K HBsAg
%K VHD RNA
%K Liver Disease
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=132093