%0 Journal Article
%T 他汀类药物在抗肿瘤药物引起的心脏毒性中的保护作用<br>Protective Effect of Statins on Cardiotoxicity Induced by Antitumor Drugs
%A 田鹏
%A 孟婷婷
%A 张钰
%A 刘安邦
%A 郑燕
%A 苏国海
%J Advances in Clinical Medicine
%P 1317-1322
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/ACM.2024.143844
%X 他汀类药物属于羟甲基戊二酰辅酶A (HMG-CoA)还原酶抑制剂，可抑制胆固醇生物合成，抗动脉粥样硬化，已经广泛用于冠状动脉粥样硬化性心脏病的治疗，近年来有研究发现他汀类药物在抗肿瘤药物所致心脏毒性中有保护作用。本文对相关报道进行综述，以期对肿瘤患者心血管损伤的预防、治疗提供思路。 <br />
Statins are hydroxymethylglutaryl-Coenzyme A (HMG-CoA) reductase inhibitors, which can inhibit cholesterol biosynthesis and anti-atherosclerosis, and have been widely used in the treatment of coronary atherosclerotic heart disease. In recent years, studies have found that statins have a pro-tective effect on cardiotoxicity caused by anti-tumor drugs. In this paper, related reports are re-viewed in order to provide ideas for the prevention and treatment of cardiovascular injury in cancer patients.
%K 他汀类药物，心脏保护，抗肿瘤药物
%K Statins
%K Cardioprotection
%K Antitumor Drug
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=83194