%0 Journal Article
%T Epidemiological, Clinical, Therapeutic and Evolutive Profile of Primary Open-Angle Glaucoma in a Cameroonian Population
%A Christelle Domngang
%A Fabiola Makamwe Tagne
%A Leonard Tedong
%A Chantal Ngoune Nanfack
%A Caroline Mvilongo
%A Giles Kagmeni
%J Open Journal of Ophthalmology
%P 93-102
%@ 2165-7416
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojoph.2024.142009
%X <p>
	<b><span style=\"font-family:;\" \"=\"\">Background:</span></b><span style=\"font-family:;\" \"=\"\"> Sub-Saharan Africa has the highest prevalence of primary open-angle
glaucoma (POAG), at 4.2%. The efficacy of medical treatment has been
demonstrated and remains one of the treatments of choice for POAG. However, in
sub-Saharan Africa, its effectiveness has many challenges, due to multiple
factors, including cost and access to care. Thus, the present study aimed to
determine</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">the
epidemiological, clinical, therapeutic and evolutive profile of primary
open-angle glaucoma patients. <b>Methodology:</b> A descriptive cross-sectional
study was carried out in two hospitals in western Cameroon. Epidemiological,
clinical, therapeutic, and evolutionary data on intraocular pressure at one
year after medical treatment were analyzed. SPSS version 23 software was used
for statistical analysis, with a significant p-value set at 5%. <b>Results:</b> A total of 201 patients with POAG were included in the study. The population
comprised 100 men and 101 women, with a mean age of 54 ¡À</span><u><span style=\"font-family:;\" \"=\"\"> </span></u><span style=\"font-family:;\" \"=\"\">12 years. At diagnosis,
the mean intraocular pressure was 23.9</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">¡À</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">8.70
mmHg for the right eye and 25.5</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">¡À</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">9.57 mmHg for the left
eye. The mean cup/disc ratio was 0.64</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">¡À</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">0.2
[0.2</span><span style=\"font-family:;\" \"=\"\">-</span><span style=\"font-family:;\" \"=\"\">1] and 0.67</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">¡À</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">0.19 [02</span><span style=\"font-family:;\" \"=\"\">-</span><span style=\"font-family:;\" \"=\"\">1] in the right and left
eyes, respectively. Monotherapy was the most prescribed treatment [59.2%].
After one year of treatment, intraocular pressure was reduced by 15.5% with
beta-blockers, 23.66% with prostaglandins, 19.11%
%K Primary Open-Angle Glaucoma
%K Medical Treatment
%K Intraocular Pressure
%K Target Intraocular Pressure
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=131885