%0 Journal Article
%T 提高难溶性中药生物利用度的技术方法<br>Technical Methods for Improving the Bioavailability of Insoluble Traditional Chinese Medicine
%A 逯文敏
%A 王向涛
%J Advances in Clinical Medicine
%P 739-749
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/ACM.2024.143765
%X 口服给药是最方便和广泛使用的药物给药方法之一。然而，许多药物由于其吸收差、口服生物利用度低而难以口服给药。根据药物溶解度和透膜性，本文介绍了低生物利用度中药成分的生物药剂学分类系统。并以提高难溶性成分的溶解度和口服吸收为立足点，综述了近年来可提高难溶性成分口服生物利用度的各类制剂技术，以期为相关新制剂的开发提供参考。<br />
Oral administration is one of the most convenient and widely used methods of drug administration. However, many drugs are difficult to administer orally due to their poor absorption and low oral bioavailability. Based on drug solubility and permeability, a biopharmaceutical classification sys-tem for low-bioavailability TCM ingredients is introduced. Based on improving the solubility and oral absorption of poorly soluble components, various preparation technologies that can improve the oral bioavailability of poorly soluble components in recent years are reviewed, in order to pro-vide a reference for the development of related new preparations.
%K 口服生物利用度，难溶性成分，生物药剂学分类，药物递送系统<br>Oral Bioavailability
%K Insoluble Ingredients
%K Classification of Biopharmaceuticals
%K Drug Delivery Sys-tem
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=82802