%0 Journal Article
%T 左金丸治疗胃食管反流病的研究进展<br>Research Progress of Zuojin Pills in the Treatment of Gastroesophageal Reflux Disease
%A 曹家琪
%A 庄田畋
%A 陆廷飞
%J Medical Diagnosis
%P 82-89
%@ 2164-5418
%D 2024
%I Hans Publishing
%R 10.12677/MD.2024.141012
%X 左金丸是中医的经典名方，出自朱丹溪《丹溪心法》，是由黄连和吴茱萸按照6:1的比例配制而成的，具有清肝泻火、降逆止呕、和胃止痛等功效，主要用于治疗肝火犯胃所致的胁痛、胃脘、胁肋胀满疼痛，嗳气，呕吐，呃逆，吞酸嘈杂等症状。近年来，关于左金丸的现代药理及作用机制的研究有很多，特别是在治疗胃食管反流病方面取得了一定的研究进展。该文从古今应用及药理机制等方面对其治疗胃食管反流病进行论述。<br />
Zuojin Pill is a classic Chinese medicine prescription, derived from Zhu Danxi’s Danxixin Method, which is formulated by Coptis and Wuzhuyu in accordance with the ratio of 6:1. It has the effects of clearing the liver and purging fire, reducing nausea and stopping vomiting, and stomach-relieving pain. It is mainly used for the treatment of hypochondriac pain, stomach distension and pain, belching, vomiting, hiccup, acid swallowing and noise caused by liver fire attacking the stomach. In recent years, there have been many researches on the modern pharmacology and mechanism of Zuojin pills, especially in the treatment of gastroesophageal reflux disease. This paper discusses its application in ancient and modern times and its pharmacological mechanism in the treatment of gastroesophageal reflux disease.
%K 左金丸，胃食管反流病，GERD，临床疗效<br>Zuojin Pills
%K Gastroesophageal Reflux Disease
%K GERD
%K Clinical Effects
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=82578