%0 Journal Article
%T Effect of flurbiprofen combined with prednisolone on interleukin-6 in elderly surgery patients
%A Jiaxin Lin
%A Hui Yang
%A Shaofen Chen
%A Jiao Xu
%J Pharmacology & Pharmacy
%P 15-26
%@ 2157-9431
%D 2024
%I Scientific Research Publishing
%R 10.4236/pp.2024.152002
%X <strong>Objective</strong><span><span><span style=\"font-family:;\" \"=\"\"><strong>:&nbsp;</strong></span></span></span><span><span><span style=\"font-family:;\" \"=\"\">To determine the effect of
flurbiprofen combined with prednisolone </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">on interleukin-6 in elderly surgery patients. </span></span></span><span><span><b><span style=\"font-family:;\" \"=\"\">Methods:</span></b></span></span><span><span><i><span style=\"font-family:;\" \"=\"\"> </span></i></span></span><span><span><span style=\"font-family:;\" \"=\"\">In this double-blind</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> <span>randomized controlled study, patients aged 65 to 80
who were undergoing spinal fusion surgery for disc herniation were administered
flurbiprofen 100</span> <span>mg (P group</span></span></span></span><span><span><span style=\"font-family:;\" \"=\"\">, </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">flurbiprofen group),
prednisolone 0.6</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">mg/kg (D group, predni</span></span></span><span><span><span style=\"font-family:;\" \"=\"\">solone group), prednisolone 0.6</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">mg/kg plus flurbiprofen 100 mg
(P</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">+</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">D</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> group</span></span></span><span><span><span style=\"font-family:;\" \"=\"\">, </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">flurbiprofen +</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">prednisolone group) or normal
saline (S group</span></span></span><span><span><span style=\"font-family:;\" \"=\"\">, </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">saline</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> <span>group)</span></span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span><span><span style=\"font-family:;\" \"=\"\">15 minutes
%K SIRS
%K Systemic Inflammatory Response Syndrome
%K IL-6
%K Interleukin-6
%K CRP
%K C-Reactive Protein
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=131260