%0 Journal Article
%T Epidemiological and Diagnostic Profile of Patients with Chronic Hepatitis B Virus from 2017 to 2021 in Parakou, Republic of Benin
%A Khadidjatou Sak¨¦
%A Cossi Angelo Attinsounon
%A Aboudou Ra£¿mi Kpossou
%A Morayo Omm Ani Salami
%A Astrid Alexandrine Hountondji
%A Kofi-Mensa Savi de Tov¨¨
%A Rhonel Ahanhanzo-Gl¨¨l¨¨
%A Kp¨¦mahoun Ren¨¦ K¨¨k¨¨
%A Sossa Edmond Gb¨¦do
%A Jean Sehonou
%A Nicolas Kodjoh
%J Advances in Infectious Diseases
%P 147-161
%@ 2164-2656
%D 2024
%I Scientific Research Publishing
%R 10.4236/aid.2024.141011
%X <strong>Introduction:</strong> Viral hepatitis B is a public health problem worldwide. The objective of this study was to determine the epidemiological and diagnostic profile of chronic carriers of hepatitis B virus seen for gastroenterology consultations in Parakou, Republic of Benin. <strong>Patients and Methods:</strong> This was a cross-sectional and descriptive study with retrospective data collection. Patients seen for gastroenterology consultations from January 1, 2017 to June 30, 2021 at the Regional Teaching Hospital of Borgou/Alibori (CHUD-B/A) and having been diagnosed as chronic carriers of hepatitis B virus were included. A minimum initial assessment was required to be included. The minimum sample size was calculated with Schwartz formula. The variable of interest was the detection of HBsAg twice and at least 6 months apart. The other variables studied were sociodemographic, clinical and paraclinical data. The data collected were analyzed using SPSS 17 software. <strong>Results:</strong> A total of 2786 patients were seen for gastroenterology consultations, including 1126 (40.4%) HBsAg-positive patients. Among them, 417 patients met the inclusion criteria and were the subject of the present study. The average age of the patients was 34.8 ¡À 10.5 years. Two hundred and forty-seven patients (65.7%) were male, representing a sex ratio of 1.9. The discovery of positive HBsAg status was made during systematic screening in 231 patients (55.4%). Scarifications were noted in 373 patients (89.4%). Asthenia was reported in 184 patients (44.1%). Co-infections with human immunodeficiency virus, hepatitis C and D viruses were 0% (0 in 92), 2.8% (4 in 146) and 14.3% (2 in 146), respectively. During the initial assessment, 274 patients (65.7%) were sero-negative for chronic HBeAg infection, 21 (5%) had clinically significant fibrosis including 16 (3.8%) at the stage of cirrhosis and 7 patients (5.4%) had hepatocellular carcinoma. <strong>Conclusion:</strong> In Parakou, chronic hepatitis B virus infection is common and affects young people with a male predominance. Asthenia is a non-specific symptom and the most reported by the patients. Around 5 out of 100 patients are seen for consultations at the stage of complication. Emphasis must be placed on early detection and subsidy for pre-therapeutic assessment.
%K Chronic Infection
%K HBV
%K Epidemiology
%K Diagnosis
%K Parakou
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=131036