%0 Journal Article
%T Influence of Omega 3 Fatty Acid Supplementation on Phase Angle Values of People Living with HIV/AIDS with Lipodystrophy Secondary to Antiretroviral Therapy: A Randomized Clinical Trial
%A Thalita Bandeira Dantas
%A Alline Peralta Castro
%A Fernando de Souza Flexa Ribeiro Filho
%A Rosana Maria Feio Libonati
%J Food and Nutrition Sciences
%P 58-70
%@ 2157-9458
%D 2024
%I Scientific Research Publishing
%R 10.4236/fns.2024.151003
%X Objective: The measurement of phase angles is an important monitoring parameter and
supplementation with omega-3 could promote benefits by modulating the
electrical potential of membranes and increasing body cell mass. This study
aimed to evaluate the effectiveness of omega-3 fatty acid supplementation on
the phase angle of people living with HIV/AIDS. Methods: In this study,
63 individuals of all genders who were undergoing outpatient follow-up and
showed lipodystrophy due to highly active antiretroviral therapy were analyzed.
Our sample consisted of two groups, one that received supplementation
containing 2550 mg of omega-3/day (1080 mg of eicosapentaenoic acid and 720 mg
of docosahexaenoic acid) for three months (n = 32) and another that underwent
nutrition guidance (n = 31). Phase angle and body cell mass were assessed for
both groups and compared at the beginning of research (T0) and after our
intervention (T1) for each group separately. Results: Phase angle
averaged 6.45¡ã ¡À 1.06 SD. The comparison between T0 and T1 showed a
significant increase in phase angle and body cell mass, whereas the guidance
group showed a decrease in body cell mass at T1 in relation to T0, with a
significant p-value. Variance in phase angle between moments showed significant
values between T0 and T1 in the supplementation group for all genders. Conclusion: Omega-3 positively modulated patients phase angle and body cell mass, but
we emphasize the need for other studies that can solidify knowledge about
supplementation dosage and intervention time.
%K HIV
%K Lipodystrophy
%K Omega-3
%K Phase Angle
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=130646