%0 Journal Article
%T 转甲状腺素蛋白淀粉样变心肌病的研究现状<br>Research Status in Transthyretin Amyloid Cardiomyopathy
%A 李帅奇
%A 凌智瑜
%J Advances in Clinical Medicine
%P 476-487
%@ 2161-8720
%D 2024
%I Hans Publishing
%R 10.12677/ACM.2024.141068
%X 转甲状腺素蛋白淀粉样变心肌病(ATTR-CM)是一种罕见的进行性衰弱性疾病。ATTR-CM主要是由于TTR淀粉样蛋白在心肌中的积聚而引起的。然而，ATTR-CM的临床表现多样且缺乏特异性，因此很容易被误诊或漏诊。目前有多种辅助检查可用于更准确地诊断该病，但它们的临床价值各不相同。尽管该病的整体预后不佳，但随着对该病的深入研究，越来越多的治疗方案正在被探索并进行临床实验。本文对转甲状腺素蛋白淀粉样变心肌病的研究现状进行了综述。<br />
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a rare, progressive and debilitating disease. ATTR-CM is mainly caused by the accumulation of TTR amyloid protein in the myocardium. Howev-er, the clinical manifestations of ATTR-CM are diverse and lack specificity, so it is easily misdiag-nosed or missed. There are a variety of tests available to more accurately diagnose the disease, but their clinical value varies. Despite the overall poor prognosis of the disease, more and more treat-ment options are being explored and undergoing clinical trials as the disease is further studied. This article reviews the research status in transthyretin amyloid cardiomyopathy.
%K 转甲状腺素蛋白淀粉样变心肌病，临床表现，诊断价值，病因治疗<br>Transthyretin Amyloid Cardiomyopathy
%K Clinical Manifestation
%K Diagnostic Value
%K Etiological Treat-ment
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=79095