%0 Journal Article
%T 长链非编码RNA与肺癌预后关系研究进展<br>Research Progress on the Relationship between Long Non-Coding RNA and Prognosis of Lung Cancer
%A 王星圆
%A 祖拉丽阿依·阿米尔
%A 戴月梅
%J Advances in Clinical Medicine
%P 18175-18181
%@ 2161-8720
%D 2023
%I Hans Publishing
%R 10.12677/ACM.2023.13112550
%X 肺癌是全球最常见的癌症，发病率和死亡率高，严重影响人类健康和生命威胁。虽然近年来其治疗取得了一定进展，但非小细胞肺癌的5年生存率仍处于较低水平。长链非编码RNA (lncRNA)作为一种不能编码蛋白质的非编码RNA分子，在多种恶性肿瘤中异常表达，且与肿瘤的预后密切相关。因此，研究lncRNA在肺癌中的表达情况，寻找与非小细胞肺癌病情进展程度有关的生物学分子标志物，对改善患者预后具有重要临床意义。本文就已发现相关lncRNA与肺癌预后关系的研究进展作一综述。<br />
Lung cancer is the most common cancer in the world, with high morbidity and mortality, seriously affecting human health and threatening life. Although its treatment has made some progress in re-cent years, the 5-year survival rate of non-small cell lung cancer is still low. Long non-coding RNA (lncRNA), as a non-coding RNA molecule that cannot encode protein, is abnormally expressed in a variety of malignant tumors and is closely related to tumor prognosis. Therefore, studying the ex-pression of lncRNA in lung cancer and searching for biological molecular markers related to the progression of NSCLC have important clinical significance for improving the prognosis of patients. In this review, we reviewed the research progress on the relationship between lncRNA and lung can-cer prognosis.
%K 长链非编码RNA，肺癌，预后，生物标志物<br>Long Non-Coding RNA
%K Lung Cancer
%K Prognosis
%K Biological Marker
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=75733