%0 Journal Article
%T Low-Dose Gamma Radiation Fields Decrease Cell Viability, Damage DNA, and Increase the Expression of Hsp70 and p53 Proteins in Human Leukocytes
%A Jessica Lizbeth Sifuentes Padilla
%A David Alejandro Garc¨ªa L¨®pez
%A Consuelo Letechipia de Le¨®n
%A Hector Rene Vega-Carrillo
%A Sergio Hugo S¨¢nchez Rodr¨ªguez
%J World Journal of Nuclear Science and Technology
%P 55-72
%@ 2161-6809
%D 2023
%I Scientific Research Publishing
%R 10.4236/wjnst.2023.134005
%X Ionizing radiations are tools in diagnosis and treatment of diseases. Leukopenia from exposure to ionizing radiation has been reported. Due to their radiosensitivity, leukocytes are a biological model to analyze cell damage. Therefore, cell viability, DNA damage, and Hsp70 and p53 expression in human leukocytes exposed to low-dose gamma radiation fields from a <sup>137</sup>Cs source were evaluated. A decrease in cell viability, DNA damage and an increase in the expression of Hsp70 and p53 proportional to the radiation dose received was found, which was 0.2, 0.4, 0.6, 0.8 and 1.0 mGy.
%K Leukocytes
%K Gamma Radiation
%K Cell Damage
%K DNA
%K Hsp70
%K p53
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=129049