%0 Journal Article
%T Non-Chemotherapy Medullary Aplasia in the Pediatric Oncology Unit of the Gabriel Touré Teaching Hospital, Bamako
%A Pierre Togo
%A Ibrahim Ahamadou
%A Tati Simaga
%A Abdoul Karim Doumbia
%A Fousseyni Traor¨¦
%A Oumar Coulibaly
%A Dj¨¦n¨¦ba Konat¨¦
%A Salif Zigm¨¦
%A Adama Demb¨¦l¨¦
%A Mohamed Elmouloud Ciss¨¦
%A Belco Ma£¿ga
%A Karamoko Sacko
%A Hawa Gouro Diall
%A Boubacar Ali Tour¨¦
%A Amadou Tour¨¦
%A Yacouba Aba Coulibaly
%A Aminata Doumbia
%A Hawa Konar¨¦
%A Kalirou Traor¨¦
%A Souleymane Sagara
%A Abdoul Aziz Diakit¨¦
%A Fatoumata Dicko
%A Cheick Bougadari Traor¨¦
%A Boubacar Togo
%J Open Journal of Pediatrics
%P 798-806
%@ 2160-8776
%D 2023
%I Scientific Research Publishing
%R 10.4236/ojped.2023.136088
%X <strong>Objectives:</strong><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> The main objective was to study the epidemiological, diagnostic and
therapeutic aspects of medullary aplasia (MA). </span><b><span style=\"font-family:Verdana;\">Methods:</span></b><span style=\"font-family:Verdana;\"> This was a
prospective and descriptive retro study conducted from January 1, 2008 to
December 31, 2018 in the pediatric oncology unit of the pediatrics department
of the Gabriel Tour¨¦ teaching Hospital in Bamako. </span><b><span style=\"font-family:Verdana;\">Results:</span></b><span style=\"font-family:Verdana;\"> We collected
29 children¡¯s cases out of 1632 admissions during the study period,
representing a frequency of 1.8% and an incidence of 2.6 cases per year. The
sex ratio was 2.6. The 11</span></span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">-</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">15 age group accounted for 45%, with an average age of 8.93 years. The
majority of fathers (55.2%) and mothers (62.1%) had received no education; they
were mainly farmers (62.1%) and housewives (86.2%). The average consultation
time was 92.21 days. Anemia was the reason for consultation in 69% of cases.
Pallor was present on admission in 96.5%; infectious syndrome accounted for
79.3%, anemic syndrome for 51.7% and hemorrhagic syndrome for 27.6%; the three
syndromes were associated in 27.6%. Malaria was associated with bone marrow
aplasia in 58.6%. Anemia was present in 93.1%, neutropenia in 65.5% and thrombocytopenia
in 86.2%. All had received a labile blood product (LBP) transfusion, and 24
(83%) had received antibiotics. Patients were treated with corticosteroids
(58.6%), an</span><span style=\"font-family:Verdana;\">drogens (20.7%) and
immunosuppressants (20.7%). The death rate was 34.6%. </span><span style=\"font-family:Verdana;\">At last count, 15
(83%) had discontinued treatment, 2 (11%) were undergoing treatment and 1 (6%)
was in remission. </span><b><span style=\"font-family:Verdana;\">Conclusion:</span></b><span style=\"font-family:Verdana;\"> Effective treatment of MA requires
improved technical facilities and better economic conditions for parents.</span></span></span></span>
%K Medullar Aplasia
%K Children
%K Bamako
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=128894