%0 Journal Article
%T 基于CRISPR/Cas系统的即时诊断研究进展<br> Progress in Point-of-Care Diagnosis Based on CRISPR/Cas System
%A 杨赛男
%A 戴斌
%A 李平
%A 刘宾
%A 王诗琪
%A 何昱嫦
%A 吕圆
%J Journal of Sensor Technology and Application
%P 493-504
%@ 2331-0243
%D 2023
%I Hans Publishing
%R 10.12677/JSTA.2023.116056
%X 面对突发公共卫生事件，快速、准确和便携的现场检测至关重要。基于CRISPR/Cas技术的分子诊断是目前现场检测主要方法，可以与多种信号传感方法相结合，集成到智能设备中，开发多个检测新平台。本文介绍基于CRISPR/Cas系统的传感器发展和现场应用，对CRISPR和现场检测的发展前景进行总结和展望。<br />
Fast, accurate and portable onsite testing is critical in the face of public health emergencies. Molecular diagnosis based on CRISPR/Cas technology is currently the main method of detection, which can be combined with a variety of signal sensing methods, integrated into smart devices, and develop multiple new detection platforms. This paper introduces the sensor development and field application based on CRISPR/Cas system, and summarizes and prospects the development prospect of CRISPR and field detection.
%K CRISPR/Cas，分子诊断，现场检测<br> CRISPR/Cas
%K Molecular Diagnostic
%K Point of Care
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=74830