%0 Journal Article
%T A Huge Metastatic Liver of a Neuroendocrin Tumor Explored by SPECT/CT with <sup>99m</sup>Tc-Tektrotyd: A Case Report
%A Imad Ghfir
%A Manal Otmani
%A Chaimae Bensaid
%A Majdouline Bellakhdar
%A Malika Ç
%A aoui
%A Nouzha BenRaï
%A s
%J Open Journal of Medical Imaging
%P 101-106
%@ 2164-2796
%D 2023
%I Scientific Research Publishing
%R 10.4236/ojmi.2023.133010
%X Background: Colorectal neuroendocrine tumors are rare and have a heterogeneous clinical representation and variable prognosis. High grade neuroendocrine tumors (NETs) are characterized by destructive and aggressive growth, followed by rapid spread. For this purpose, SPECT/CT with 99mTc-Tektrotyd is very useful for imaging and staging of NETs. Case Report: A 50-year-old man with a huge metastatic liver from an unknown neuroendocrine tumor (NET). SPECT/CT with 99mTc-Tektrotyd was performed in this patient, it showed a huge metastatic hepatomegaly compressing neighboring organs with bone metastases, and also revealed the primary colon tumor. Discussion and Conclusion: In recent decades, the incidence and prevalence of neuroendocrine tumors (NETs), especially those of the colorectal segments, have been increasing. 99mTc-EDDA/HYNIC-TOC (Tektrotyd?) was introduced into the market and its use has been approved for scintigraphic imaging of patients with NETs and other SSTR-positive tumors. It provides in vivo metabolic data related to the over-expression of Somatostatin Receptors (SSTRs) and also predicts response to peptide receptor radionuclide therapy (PRRT).
%K Colonic Neuroendocrine Tumor
%K Liver Metastases
%K Bone Metastases
%K SPECT/CT
%K <
%K sup>
%K 99m<
%K /sup>
%K Tc-Tektrotyd
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=127039