%0 Journal Article
%T 预防双膦酸盐相关性颌骨坏死的研究进展<br>Research Progress in the Prevention of Bisphosphonate-Related Jaw Necrosis
%A 扈超越
%A 俞燕玲
%A 陈燕玲
%A 祁周妙
%A 刘凯
%J Advances in Clinical Medicine
%P 12439-12447
%@ 2161-8720
%D 2023
%I Hans Publishing
%R 10.12677/ACM.2023.1381743
%X 双膦酸盐类药物较广泛地应用于临床骨质疏松的治疗和癌症患者骨转移的抑制，特别是近年来随着对双膦酸盐类药物副作用的认识进一步增加，双膦酸盐相关性颌骨坏死的严重性也越来越受到人们的重视。但由于目前缺乏明确的治疗措施，因此对于此疾病的预防至关重要。本论文综述了预防药物性颌骨坏死的研究进展，重点关注了策略和前沿领域，旨在提供对该疾病的更深入理解和有效管理的指导。<br />
In recent years, there has been growing recognition of the side effects associated with bisphospho-nate drugs, which are widely used in the treatment of clinical osteoporosis and the inhibition of bone metastasis in cancer patients. One of the severe side effects is bisphosphonate-related oste-onecrosis of the jaw (BRONJ), and its severity has been increasingly emphasized. However, the lack of definitive treatment measures makes prevention of this condition crucial. This paper aims to provide a comprehensive review of the research progress in preventing drug-induced osteonecrosis of the jaw, focusing on strategies and emerging areas. The goal is to offer guidance for a deeper un-derstanding and effective management of this condition.
%K 双膦酸盐，颌骨坏死，流行病学，发生机制，危险因素，治疗，预防措施<br>Bisphosphonates
%K Necrosis of Jaw
%K Epidemiology
%K Pathogenetic Mechanism
%K Risk Factors
%K Treatment
%K Preventive Measure
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=70366